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Blood DisordersCancer

Blood & Marrow Transplant (BMT) Clinic

The Bone Marrow Transplant, Cellular and Gene Therapy Program provides life-saving therapies for children with a variety of conditions, including blood cancers; noncancerous blood conditions, such as primary immune deficiency disorders, sickle cell disease, beta thalassemia and aplastic anemia; brain tumors and other solid tumors; and certain rare metabolic and genetic disorders.

These cutting-edge therapies often involve providers from many specialties. Drawing on expertise across multiple disciplines allows us to deliver optimal care before, during and after the course of treatment.

Why families choose us

Outstanding bone marrow transplant (BMT or stem cell transplant) outcomes

  • Our BMT patients have among the highest survival rates in the nation, thanks to our commitment to thorough pretransplant evaluation and preparation and post-transplant follow-up care.  

Pioneers in cellular therapies

  • We were the first medical center in California certified to deliver CAR T-cell therapy to pediatric patients outside of a clinical trial.

Leaders in gene therapy

  • UCSF was one of the first medical centers to offer newly-approved gene therapies for sickle cell disease and is at the forefront of research into potentially curative gene-correcting treatments.

Commitment to success

Support for families 

Recognizing that optimal care isn't just about treating a disease, our program is designed to ease the medical journey for patients and families:

  • We work to provide seamless care, both within and outside our local communities, serving patients and referring doctors well beyond the San Francisco Bay Area, thanks to our comprehensive telehealth system. 
  • Specialized multidisciplinary clinics ensure that patients with rare metabolic disorders or severe graft-versus-host disease get the comprehensive care and support they need.
  • Dedicated patient navigators help families with managing referrals, insurance concerns and appointment planning.

Awards & recognition

  • Top 10 in the nation and best in Northern California for cancer care

  • Ranked among the nation's best in 11 specialties

  • Designated an early phase clinical trials core site by the Children's Oncology Group

  • Accredited by the Foundation for Accreditation of Cellular Therapy

Our locations (2)

    Our team

    Plan your visit

    For visitors

    Before you head to the hospital, check out our guidelines for visitors and caregivers.

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    Your Stay

    We offer valuable information to help you plan for your child's upcoming hospital stay. Find out about food services, family accommodations and more.

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    Your Child's Care Team

    Our doctors, nurses, child life specialists and other providers have special training to care for children. Meet your child's care team.

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    Interpreter Services & Communication Assistance

    Interpreter services in many languages and TDDs are available for families that need help communicating with care teams. Here's how to access them.

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    Related clinics (7)

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    Comprehensive Sickle Cell Center

    Comprehensive Sickle Cell Center

    747 52nd St.
    Oakland, CA 94609

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    Hematology Clinic

    Hematology Clinic

    San Francisco / Fresno / Greenbrae / Oakland / Santa Rosa / Walnut Creek
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    Immunology Center

    Immunology Center

    1825 Fourth St., Sixth Floor
    San Francisco, CA 94158

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    Oncology Program

    Oncology Program

    San Francisco / Oakland / Walnut Creek

    Primary Immune Regulatory Disorder (PIRD) Clinic

    Primary Immune Regulatory Disorder (PIRD) Clinic

    1825 Fourth St., Sixth Floor
    San Francisco, CA 94158

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    Survivorship Program

    Survivorship Program

    Oakland / San Francisco
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    Thalassemia Center

    Thalassemia Center

    747 52nd St.
    Oakland, CA 94609

    Support services

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    Child Life Services

    Activity rooms, pet therapy and more to help kids feel at home.

    Child Life

    Certified child life specialists ease the stress and anxiety of childhood illness through therapeutic play, schooling and family-focused support.

    Family Amenities

    Family-friendly amenities help you relax and take care of yourself while staying close to your child. We offer lounges, kitchens, showers, breastfeeding rooms and more.

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    Social Services

    Social workers ease the effect of illness, injury and hospitalization on your family with counseling and assistance to help you navigate the challenges.

    activity-rooms-2x

    Activity Rooms

    Activity rooms offer a relaxed environment for children of all ages. Features include a playroom, digital arts studio and teen lounge. Find out more.

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    Art Therapy

    Art therapy helps kids and families express themselves, making it easier to cope with pediatric health issues. Group and bedside services are available.

    music-program-2x

    Music Therapy Program

    Board-certified music therapists help kids cope with illness and the feelings that come with it. Find out about group activities and bedside therapy.

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    School Program

    Our schoolroom services and individual learning programs help children hospitalized at UCSF continue their education and get ready to return to school.

    school-re-entry-program-2x

    School Re-Entry Program

    We help kids return to school after hospitalization by educating staff and students about their needs and recommending needed accommodations. Read more.

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    Individual Playtime & Instruction

    If your child can't be around other kids for medical reasons, you can sign up for private sessions in our activity and school rooms. Find out how.

    interpreters-2x

    Interpreter Services & Communication Assistance

    Interpreter services in many languages and TDDs are available for families that need help communicating with care teams. Here's how to access them.

    Family Resource Center

    We help families cope with the challenges of childhood illness and hospitalization in a relaxing environment where parents can get a much-needed break.

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    Parent Support Program

    Weekly activities, including knitting, scrapbooking, chair massage and more, help family caregivers get a much-needed break. Find out more.

    patient-relations-2x

    Patient Relations

    Patient relations reps and nursing supervisors are here to answer questions and address concerns. Learn about your rights, how to reach us and more.

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    Spiritual Care

    Chaplains help UCSF patients, families and staff cope with the spiritual and emotional challenges of childhood illness. Learn more.

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    International Services

    If you're coming to UCSF from outside the U.S., we coordinate your child's appointments and provide other helpful services. Here's how to get started.

    Patient stories

    Sisters bond over lifesaving transplant

    Jade became sick overnight with a potentially fatal blood disorder. Despite the odds, her big sister, Ava, was a perfect match as a donor.

    Precision treatment helps kids with blood cancer

    A cutting-edge therapy developed at UCSF minimizes the amount of chemotherapy kids like Astrid King need to beat blood cancer.

    Read Astrid's story

    Meet UCSF's first CAR T-cell patient

    Shaun had been battling an aggressive leukemia for six years. When his care team recommended a new experimental treatment, his parents described it as "divine intervention."

    Decorative Caduceus

    A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (C...

    The primary objective of this access and distribution protocol is to examine the incidence of neutrophil recovery of ≥500/mm3 after cord blood transplantation in a multi-institution setting using CBUs that are not FDA licensed.

    Recruiting

    More about this study
    Decorative Caduceus

    Autologous Gene Therapy for Artemis-Deficient SCID

    Patient survival status and (if applicable) cause of death will be recorded to assess overall survival.

    Recruiting

    More about this study
    Decorative Caduceus

    A Feasibility Study Using CLINIMACS® for Alpha/Beta T-Cell Depletion in Stem Cell Transplant

    The cumulative incidence of Grade III-IV acute GVHD at Day 100 will be summarized by incidence curves. GVHD evaluations will be performed using standard criteria.37 Patients with graft rejection will be censored.

    Recruiting

    More about this study
    Decorative Caduceus

    A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Trans...

    Clinically significant CMV is defined as the first of (1) initiation of anti-CMV preemptive therapy for documented CMV DNAemia or (2) onset of CMV end-organ disease. Will estimate the cumulative incidence of clinically significant...

    Recruiting

    More about this study
    Decorative Caduceus

    Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoi...

    The adverse event rate will be summarized using descriptive statistics, together with 95% confidence intervals where appropriate. No formal statistical hypothesis testing will be performed. Adverse events defined: failure of engra...

    Recruiting

    More about this study
    Decorative Caduceus

    Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

    to assess overall response rate following chemoimmunotherapy induction therapy

    Recruiting

    More about this study
    Decorative Caduceus

    EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection

    Patients will be monitored for adverse events related to the infusion of EBV CTLs

    Recruiting

    More about this study
    Decorative Caduceus

    Stress Hydrocortisone In Pediatric Septic Shock

    Appearance of new or progression of existing organ dysfunctions according to PELOD-2 definitions. PELOD-2 considers 5 organ dysfunctions (neurological, cardiovascular, renal, respiratory, and hematological) with 10 total variables...

    Recruiting

    More about this study
    Decorative Caduceus

    Childhood Cancer Survivor Study

    Recruiting

    More about this study
    Decorative Caduceus

    Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children

    Duration of hospitalization in days for enrolled subjects

    Recruiting

    More about this study
    See all clinical trials

    Our research initiatives

    • ucsf-division-of-allergy-immunology-and-bmt-research-2x

      UCSF Division of Allergy, Immunology & BMT Research

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    • ucsf-childrens-cancer-program-clinical-trials-2x

      Clinical Trials at UCSF: Pediatric Cancer

      Learn more

    • Early-Phase Clinical Trials at UCSF: Pediatric Cancer

      Learn more

    Resources for physicians

    Whether you're referring a patient, seeking a second opinion or looking for professional education opportunities, you'll find resources on the UCSF Pediatric Cancer Program's MedConnection hub. We look forward to partnering with you!

    Smell the roses

    Wander outside into our Butterfly Garden in Oakland and our healing gardens at Mission Bay.

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