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Blood Disorders

Comprehensive Sickle Cell Center

(510) 428-3372

The UCSF Comprehensive Sickle Cell Center on our Oakland campus is the largest and most complete program for individuals with sickle cell disease and their families in the western United States. Our center has been at the forefront of research into better treatments and potential cures for the disease since its establishment in 1973.

We provide diagnosis, treatment and long-term management for patients of all ages, from babies to adults. Our team of specialists includes hematologists, pediatricians, internists, nurse practitioners, registered nurses, genetic counselors, social workers, psychologists and community health workers.

At UCSF Benioff Children's Hospitals, our goal is to help individuals with sickle cell disease and their families achieve the best possible quality of life. We work with each patient and family to develop comprehensive treatment plans and find appropriate strategies for minimizing symptoms and complications. Our psychosocial team can help with advocating to have any special needs met at school or work and with finding additional resources.

In sickle cell disease, a genetic (inherited) defect changes the shape of red blood cells from round to a "C," or sickle, shape. Anemia develops because the C-shaped red blood cells can't carry enough oxygen to the body's organs. Those misshapen cells also get stuck in tiny blood vessels, leading to pain and serious problems.

Early diagnosis and care can slow or prevent some complications. We offer the latest treatments, including hydroxyurea, the first successful medical therapy for the disease, and bone marrow transplantation. We also focus on effective pain management, making individualized pain plans and offering complementary therapies, such as virtual reality massage, biofeedback and acupuncture. In addition, because we are active in research, our patients often have opportunities to take part in clinical trials (studies of promising new treatments).

Care for sickle cell disease is also available at our pediatric Hematology Clinics in San Francisco (at Mission Bay), Oakland, Walnut Creek and Santa Rosa.

Our locations (1)

    Our team

    Awards & recognition

    • U S News and World Report badge recognizing UCSF Benioff among the Best Children's Hospitals Ranked in 11 Specialties, 2024-2025

      Ranked among the nation's best in 11 specialties

    Recommended reading

    12-tips-parents-of-kids-with-sickle-cell-should-know-2x

    Raising a Child with Sickle Cell Disease: Tips for Parents

    If your child has sickle cell disease, these tips can help you monitor their health, prevent illness and know when to call your child's doctor.

    Plan your visit

    Preparing for your appointment

    What to Bring

    • Photo I.D.
    • Health insurance card
    • Insurance authorization, if required
    • Doctor's referral, if required
    • Recent test results related to your child's condition
    • List of medications, including dosages, plus any your child is allergic to
    • List of questions you may have
    • Device or paper for taking notes

    For visitors

    Before you head to the hospital, check out our guidelines for visitors and caregivers.

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    Your Stay

    We offer valuable information to help you plan for your child's upcoming hospital stay. Find out about food services, family accommodations and more.

    Learn more
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    Your Child's Care Team

    Our doctors, nurses, child life specialists and other providers have special training to care for children. Meet your child's care team.

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    Interpreter Services & Communication Assistance

    Interpreter services in many languages and TDDs are available for families that need help communicating with care teams. Here's how to access them.

    Learn more

    Related clinics (3)

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    Hematology Clinic

    Hematology Clinic

    San Francisco / Fresno / Greenbrae / Oakland / Santa Rosa / Walnut Creek
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    Hemoglobinopathy Lab

    Hemoglobinopathy Lab

    747 52nd St.
    Oakland, CA 94609

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    Infusion Center

    Infusion Center

    San Francisco / Oakland / Walnut Creek

    Partner clinic (1)

    3

    Stad Center for Pediatric Pain, Palliative & Integrative Medicine

    Stad Center for Pediatric Pain, Palliative & Integrative Medicine

    San Francisco / Oakland / Walnut Creek

    Support services

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    Child Life Services

    Activity rooms, pet therapy and more to help kids feel at home.

    Child Life

    Certified child life specialists ease the stress and anxiety of childhood illness through therapeutic play, schooling and family-focused support.

    Family Amenities

    Family-friendly amenities help you relax and take care of yourself while staying close to your child. We offer lounges, kitchens, showers, breastfeeding rooms and more.

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    Social Services

    Social workers ease the effect of illness, injury and hospitalization on your family with counseling and assistance to help you navigate the challenges.

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    Activity Rooms

    Activity rooms offer a relaxed environment for children of all ages. Features include a playroom, digital arts studio and teen lounge. Find out more.

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    Art Therapy

    Art therapy helps kids and families express themselves, making it easier to cope with pediatric health issues. Group and bedside services are available.

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    Music Therapy Program

    Board-certified music therapists help kids cope with illness and the feelings that come with it. Find out about group activities and bedside therapy.

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    School Program

    Our schoolroom services and individual learning programs help children hospitalized at UCSF continue their education and get ready to return to school.

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    School Re-Entry Program

    We help kids return to school after hospitalization by educating staff and students about their needs and recommending needed accommodations. Read more.

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    Individual Playtime & Instruction

    If your child can't be around other kids for medical reasons, you can sign up for private sessions in our activity and school rooms. Find out how.

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    Interpreter Services & Communication Assistance

    Interpreter services in many languages and TDDs are available for families that need help communicating with care teams. Here's how to access them.

    Family Resource Center

    We help families cope with the challenges of childhood illness and hospitalization in a relaxing environment where parents can get a much-needed break.

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    Parent Support Program

    Weekly activities, including knitting, scrapbooking, chair massage and more, help family caregivers get a much-needed break. Find out more.

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    Patient Relations

    Patient relations reps and nursing supervisors are here to answer questions and address concerns. Learn about your rights, how to reach us and more.

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    Spiritual Care

    Chaplains help UCSF patients, families and staff cope with the spiritual and emotional challenges of childhood illness. Learn more.

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    International Services

    If you're coming to UCSF from outside the U.S., we coordinate your child's appointments and provide other helpful services. Here's how to get started.

    Smell the roses

    Wander outside into our Butterfly Garden in Oakland and our healing gardens at Mission Bay.

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