Choroid Plexus Tumors
Treatment

A choroid plexus tumor is a serious condition that needs to be treated by a multi-disciplinary team consisting of neurosurgeons, neuro-oncologists and radiation oncologists. Even with appropriate treatment, a fraction of patients die from this disease.

As with most tumors, our treatments are limited to three modalities: surgery, radiation and chemotherapy.

Surgery

Surgical removal is the most effective treatment for choroid plexus tumors. Surgery often cures choroid plexus papillomas, and patients with choroid plexus carcinomas have improved outcomes when the tumors can be completely removed.

Choroid plexus tumors often contain many blood vessels. In some circumstances, surgery can be made safer if the blood supply to the tumor is closed, using a technique called embolization, before the actual surgery.

Chemotherapy

Aggressive chemotherapy, with or without high dose chemotherapy with stem cell rescue, is often used in patients with choroid plexus carcinomas. Several small studies appear to show this improves outcomes, especially in patients who were unable to have the tumor completely removed with surgery.

Radiation

Radiation can be an effective treatment for choroid plexus carcinomas. However, high doses can be toxic to the developing brains of young children. Radiation therapy is often reserved for patients whose tumors have recurred after initial treatment, or for those with metastatic disease who do not respond to chemotherapy.

Reviewed by health care specialists at UCSF Benioff Children's Hospital.

Related Information

UCSF Clinics & Centers

Pediatric Brain Center

Pediatric Brain Tumor Center
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-2986
Fax: (415) 353-2657
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Neurosurgery Clinic
1825 Fourth St., Fifth Floor, 5A
San Francisco, CA 94158
Phone: (415) 353-7500
Fax: (415) 353-2889
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