Skip to Main Content

Pediatric Hereditary Cancer Clinic

The UCSF Pediatric Hereditary Cancer Clinic cares for children and families with genetic mutations that increase their risk for cancer.

Our services include:

  • Genetic counseling and testing for patients and their families
  • Personalized recommendations for long-term monitoring based on genetic test results and family history
  • Coordination of follow-up care, including cancer prevention and monitoring, with referrals to other UCSF specialty clinics, as needed

This clinic is part of the UCSF Pediatric Cancer Program. Our team of providers includes genetic counselors and pediatric oncologists, as well as a medical geneticist (a doctor who specializes in care for genetic disorders), nurse coordinator and patient navigator. We are dedicated to meeting the unique needs of families who carry mutations linked to hereditary cancers, including by helping them navigate both the psychological and the medical aspects of having an increased cancer risk.

What to expect

If previous genetic testing has shown that your child carries a mutation associated with hereditary cancer, our team will review the findings, talk to you about recent medical research related to your situation, and describe current recommendations for cancer monitoring and prevention. Your child's provider will conduct a physical exam and ask questions to better understand the medical history, including details on the birthing parent's pregnancy and the child's birth and early development. We may recommend additional screening exams or consultations with other specialists.

If your child hasn't had genetic testing, we will review the medical records, collect details on your family health history and give you information on hereditary cancer. We can help you weigh the potential benefits and limitations of testing as you decide whether it's right for your family.

For genetic testing, we typically swab the inside of the cheek or collect a blood sample, then send it to a specialized laboratory where it's tested for mutations associated with a higher chance of developing specific cancers. In some cases, your genetic counselor may recommend additional testing for your child or offer genetic testing to other family members.

As the scientific understanding of hereditary cancer improves, our knowledge and recommendations continue to evolve. We invite each of our patients to enroll in a long-term study that uses your information anonymously in research on hereditary cancer. As part of this study, we will periodically send you updates on relevant advances and also request occasional updates about your family. Our team can tell you more about this and other research opportunities during your appointment.

Before your appointment

We will email you a link to a family history questionnaire or, if you prefer, mail you a paper copy. Please complete the questionnaire before your appointment.

Please send us a copy of the results of any previously performed genetic testing for your child or biologically related family members. If you have difficulty getting the original lab reports, contact our office for assistance.

Our locations (1)

    Awards & recognition

    • Best in Northern California for cancer care

    • Ranked among the nation's best in 10 specialties

    Plan your visit

    Preparing for your appointment

    What to Bring

    • Photo I.D.
    • Health insurance card
    • Insurance authorization, if required
    • Doctor's referral, if required
    • Recent test results related to your child's condition
    • List of medications, including dosages, plus any your child is allergic to
    • List of questions you may have
    • Device or paper for taking notes

    Related clinics (4)

    cancer-genetics-and-prevention-program-320x320-2x 2

    Cancer Genetics & Prevention Program

    Cancer Genetics & Prevention Program

    San Francisco

    medical-genetics-and-genomics-clinic-320x320-2x 2

    Medical Genetics & Genomics Clinic

    Medical Genetics & Genomics Clinic

    San Francisco / Oakland

    oncology-clinic-320x320-2x 3

    Oncology Clinic

    Oncology Clinic

    San Francisco / Oakland / Walnut Creek

    oncology-clinic-320x320-2x

    Precision Cancer Medicine Program

    Precision Cancer Medicine Program

    1825 Fourth St., Sixth Floor
    San Francisco, CA 94158

    Support services

    Child Life Services

    Activity rooms, pet therapy and more to help kids feel at home.

    Child Life

    Certified child life specialists ease the stress and anxiety of childhood illness through therapeutic play, schooling and family-focused support.

    beads-of-courage-2x

    Beads of Courage

    We help children cope with cancer testing and treatment challenges by awarding colorful beads for each milestone they achieve. Find out about our program.

    camp-okizu-2x

    Camp Okizu

    This overnight summer camp for children with cancer, siblings and families offers fun activities, education sessions and support in a beautiful setting.

    individual-playtime-and-tutoring-2x

    Individual Playtime & Instruction

    If your child can't be around other kids for medical reasons, you can sign up for private sessions in our activity and school rooms. Find out how.

    activity-rooms-2x

    Activity Rooms

    Activity rooms offer a relaxed environment for children of all ages. Features include a playroom, digital arts studio and teen lounge. Find out more.

    art-therapy-program-2x

    Art Therapy

    Art therapy helps kids and families express themselves, making it easier to cope with pediatric health issues. Group and bedside services are available.

    music-program-2x

    Music Therapy Program

    Board-certified music therapists help kids cope with illness and the feelings that come with it. Find out about group activities and bedside therapy.

    school-program-2x

    School Program

    Our schoolroom services and individual learning programs help children hospitalized at UCSF continue their education and get ready to return to school.

    school-re-entry-program-2x

    School Re-Entry Program

    We help kids return to school after hospitalization by educating staff and students about their needs and recommending needed accommodations. Read more.

    Family Amenities

    Family-friendly amenities help you relax and take care of yourself while staying close to your child. We offer lounges, kitchens, showers, breastfeeding rooms and more.

    social-services-2x

    Social Services

    Social workers ease the effect of illness, injury and hospitalization on your family with counseling and assistance to help you navigate the challenges.

    interpreters-2x

    Interpreter Services & Communication Assistance

    Interpreter services in many languages and TDDs are available for families that need help communicating with care teams. Here's how to access them.

    Family Resource Center

    We help families cope with the challenges of childhood illness and hospitalization in a relaxing environment where parents can get a much-needed break.

    family-support-program-2x

    Parent Support Program

    Weekly activities, including knitting, scrapbooking, chair massage and more, help family caregivers get a much-needed break. Find out more.

    patient-relations-2x

    Patient Relations

    Patient relations reps and nursing supervisors are here to answer questions and address concerns. Learn about your rights, how to reach us and more.

    spiritual-care-2x

    Spiritual Care

    Chaplains help UCSF patients, families and staff cope with the spiritual and emotional challenges of childhood illness. Learn more.

    international-services-2x

    International Services

    If you're coming to UCSF from outside the U.S., we coordinate your child's appointments and provide other helpful services. Here's how to get started.

    Decorative Caduceus

    Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

    To measure the response of treatments chosen based on: • Event free survival (EFS)

    Recruiting

    More about this study
    Decorative Caduceus

    Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma

    To evaluate the efficacy of difluoromethylornithine (DFMO) in combination with etoposide in patients with relapsed/refractory neuroblastoma, based upon: o Event free survival (EFS) from time of enrollment.

    Recruiting

    More about this study
    Decorative Caduceus

    Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

    Measured by the presence of radiologically assessable disease by cross-sectional computed tomography (CT) or Magnetic resonance imaging (MRI) imaging and/or by metaiodobenzylguanidine (MIBG) or positron emission tomography (PET) s...

    Recruiting

    More about this study
    Decorative Caduceus

    Neuroblastoma Maintenance Therapy Trial

    Recruiting

    More about this study
    Decorative Caduceus

    Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarco...

    Estimated four year thoracic event free survival (tEFS) where tEFS is calculated as the time from study enrollment. Any recurrence within the pulmonary parenchyma, involving the pleural surface or the drain/surgical site wound wil...

    Recruiting

    More about this study
    Decorative Caduceus

    Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusi...

    The Kaplan-Meier method will be used to estimate 3-year FFS along with 80% log-minus-log transformed confidence limits for very low risk (VLR) patients.

    Recruiting

    More about this study
    Decorative Caduceus

    Project: Every Child for Younger Patients With Cancer

    The number of patients who agree to be in the Biobanking part of the study and have leftover tumor tissue and some normal blood, bone marrow, or other tissue saved for future research.

    Recruiting

    More about this study
    Decorative Caduceus

    Project: Every Child for Younger Patients With Cancer

    The number of patients who agree to be in the Biobanking part of the study and have leftover tumor tissue and some normal blood, bone marrow, or other tissue saved for future research.

    Recruiting

    More about this study
    Decorative Caduceus

    Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusi...

    The Kaplan-Meier method will be used to estimate 3-year FFS along with 80% log-minus-log transformed confidence limits for very low risk (VLR) patients.

    Recruiting

    More about this study
    Decorative Caduceus

    Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Adva...

    Will be estimated over time and considered in relationship to changes in treatment trial cohort status (activations, suspensions, terminations).

    Recruiting

    More about this study
    See all clinical trials

    Fetal surgery firsts

    The first open fetal surgery in the world was performed at UCSF in the early 1980s.

    Share