Beckwith-Wiedemann Syndrome

Treatment varies from child to child, depending on what characteristics the baby has and how severe they are. Treatments may include:

  • In newborns, treatment for low blood sugar, or hypoglycemia, is important to reduce the risk of central nervous system complications, which can result from insufficient nutrition to the brain.
  • Newborns with defects in the abdominal wall will have the defect repaired.
  • Infants with an insufficient airway (due to a large tongue) may need a breathing tube.
  • Since large tongues can interfere with feeding, some children may need to be fed with special nipples or given tube feedings.
  • Children should be screened for tumors, using abdominal ultrasound and serum alpha fetoprotein (AFP), every three months until 8 years of age, and tumors should be treated as needed.
  • Children with very enlarged tongues may benefit from surgery to reduce the size of the tongue at 2 to 4 years of age. This procedure can lead to improved feeding and speech.
  • Some children benefit from speech therapy.
  • Surgery may be performed during puberty to equalize different leg lengths. Surgery may help with facial growth differences as well; the age when these surgeries are performed depends on the child's specific case.
  • Orthodontic treatment is usually needed in adolescence.

Reviewed by health care specialists at UCSF Benioff Children's Hospital.

Related Information

UCSF Clinics & Centers

Craniofacial Center
1825 Fourth St., Fifth Floor, 5C
San Francisco, CA 94158
Phone: (415) 476-2271
Fax: (415) 476-9513
Appointment information