The Immunogenetics and HLA Laboratory provides human leukocyte antigen (HLA) typing, HLA antibody identification, and post-transplant engraftment monitoring services for patients at UCSF Benioff Children's Hospitals.
Immunogenetics & HLA Lab
These are required for kids who:
- Are recipients of bone marrow/stem cell transplants
- Are being evaluated for organ transplantation
- Require platelet transfusions from HLA-matched donors
- Are being evaluated for conditions with known associations to particular HLA alleles
License and accreditation
As a licensed California State Clinical Histocompatibility Laboratory, we have provided "gold standard" molecular immunogenetics analysis since 1996. The lab is internationally respected in assay development and research on the role of HLA and natural killer cell immunoglobulin-like receptor (KIR) genetics in disease association and stem-cell transplantation, and an international leader in the field of next-generation sequencing (NGS) of HLA.
We are accredited by the American Society for Histocompatibility and Immunogenetics (ASHI) and the Clinical Laboratory Improvement Act (CLIA).
What is immunogenetics?
Immunogenetics is an area of medicine that focuses on the connection between the immune system and genetics (the study of heredity). It's defined by Merriam-Webster as "a branch of immunology concerned with the interrelations of heredity, disease, and the immune system and its components."
Center for Applied Genomics (CAG)
Research here focuses on discovering the genetic causes of childhood diseases and translating those findings into medical innovations.
Molecular Diagnostics Lab
This laboratory uses technologies and procedures to evaluate infectious disease, inherited disorders, oncogene copy number and other gene abnormalities.
Molecular Genetics Lab
We offer state-of-the-art genetic testing along with a team of pediatric experts who provide comprehensive interpretation of test results.
Soothing the soul