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The Center for Applied Genomics (CAG) at UCSF Benioff Children’s Hospital Oakland Research Institute (CHORI) is a genome center devoted to biological and medical research.
We focus on using functional genomic approaches to prevent and predict the evolution of disease and response to therapy. Our aim is to discover the genetic causes of common childhood diseases and translate findings into medical innovations.
(510) 450-7600
(510) 450-7910
5700 Martin Luther King Jr. Way
Oakland, CA 94609
CAG's genetic and genomic research emphasizes next-generation sequencing (NGS). Work at our center ranges from basic research to diagnostics, drug discovery and applications to public health.
We provide high-quality Next-Generation (Next-Gen) sequencing data quickly, and at a reasonable cost. To request an information packet, email [email protected].
Our facility offers state-of-the-art, Next-Gen services on the 454 GS-FLX+ Titanium sequencing platform, which can be used to support research projects. We specialize in sequencing genes from pooled amplicons of immunogenetic complexes, including the human leukocyte antigen (HLA) and genes involved in cardiomyopathies.
By using amplicon-based Next-Gen technologies, we can provide fast and economical genomic research sequence support for immunogenomics, disease association, pharmacogenetics, population genetics and personalized medicine studies.
Among other services, we provide:
Our amplicon sequencing is based on ultra-deep sequencing of PCR products and can be used for analyzing genetic variations within a population. The long-read lengths and data accuracy of Roche GS FLX+ makes the technology the gold standard for amplicon sequencing. Because each molecule in a pool of amplicons can be sequenced individually, the technology has the power to detect rare variants with detection limits of at least 0.5 percent.
