Tippi Mackenzie, MD

Fetal and pediatric surgeon

Dr. Tippi MacKenzie, a pediatric surgeon at UCSF Benioff Children's Hospital and its Fetal Treatment Center, has special interests in fetal surgery, advanced laparoscopy, and endocrine and biliary surgery. She is a member of the Biomedical Sciences Program and Institute for Regeneration Medicine, with a research focus on stem cell transplantation in utero to treat genetic disease.

MacKenzie earned a medical degree at Stanford University and completed a general surgery residency at Brigham and Women's Hospital in Boston. She completed a pediatric surgery fellowship at the Children's Hospital of Philadelphia, where she held a clinical appointment in general, thoracic and fetal surgery.

Clinics

Fetal Treatment Center
1855 Fourth St., Second Floor, Room A-2432
San Francisco, CA 94158
Phone: (800) 793-3887
Fax: (415) 502-0660

Pediatric Surgery Clinic
1825 Fourth St., Fifth Floor, 5B
San Francisco, CA 94158
Phone: (415) 476-2538
Fax: (415) 476-2929

Conditions & Treatments

More about Tippi Mackenzie

Education

Stanford School of Medicine 1997

Residencies

Brigham and Women's Hospital, Surgery 1999
Children's Hospital of Philadelphia, Pediatric Surgery 2002

Fellowships

Children's Hospital of Philadelphia, Pediatric Surgery 2007

Selected Research and Publications

  1. Vora B, Wang A, Kosti I, Huang H, Paranjpe I, Woodruff TJ, MacKenzie T, Sirota M. Meta-Analysis of Maternal and Fetal Transcriptomic Data Elucidates the Role of Adaptive and Innate Immunity in Preterm Birth. Front Immunol. 2018; 9:993.
  2. Frascoli M, Coniglio L, Witt R, Jeanty C, Fleck-Derderian S, Myers DE, Lee TH, Keating S, Busch MP, Norris PJ, Tang Q, Cruz G, Barcellos LF, Gomez-Lopez N, Romero R, MacKenzie TC. Alloreactive fetal T cells promote uterine contractility in preterm labor via IFN-? and TNF-a. Sci Transl Med. 2018 Apr 25; 10(438).
  3. Witt RG, Kreger EM, Buckman LB, Moradi PW, Ho PT, Derderian SC, Tsai P, Baker C, Schramm N, Cleary R, Garcia JV, MacKenzie TC. Systemic multilineage engraftment in mice after in utero transplantation with human hematopoietic stem cells. Blood Adv. 2018 Jan 09; 2(1):69-74.
  4. Chumfong I, Lee H, Padilla BE, MacKenzie TC, Vu LT. Esophagoesophagopexy technique for assisted fistulization of esophageal atresia. Pediatr Surg Int. 2018 Jan; 34(1):63-69.
  5. Berger VK, Sparks TN, Jelin AC, Derderian C, Jeanty C, Gosnell K, Mackenzie T, Gonzalez JM. Non-Immune Hydrops Fetalis: Do Placentomegaly and Polyhydramnios Matter? J Ultrasound Med. 2018 May; 37(5):1185-1191.
  6. Padilla BE, Vu L, Lee H, MacKenzie T, Bratton B, O'Day M, Derderian S. Sacrococcygeal teratoma: late recurrence warrants long-term surveillance. Pediatr Surg Int. 2017 Nov; 33(11):1189-1194.
  7. Witt R, MacKenzie TC, Peranteau WH. Fetal stem cell and gene therapy. Semin Fetal Neonatal Med. 2017 Dec; 22(6):410-414.
  8. Steurer MA, Peyvandi S, Baer RJ, MacKenzie T, Li BC, Norton ME, Jelliffe-Pawlowski LL, Moon-Grady AJ. Epidemiology of Live Born Infants with Nonimmune Hydrops Fetalis-Insights from a Population-Based Dataset. J Pediatr. 2017 Aug; 187:182-188.e3.
  9. Kreger EM, Singer ST, Witt RG, Sweeters N, Lianoglou B, Lal A, Mackenzie TC, Vichinsky E. Favorable outcomes after in utero transfusion in fetuses with alpha thalassemia major: a case series and review of the literature. Prenat Diagn. 2016 Dec; 36(13):1242-1249.
  10. Beaudin AE, Boyer SW, Perez-Cunningham J, Hernandez GE, Derderian SC, Jujjavarapu C, Aaserude E, MacKenzie T, Forsberg EC. A Transient Developmental Hematopoietic Stem Cell Gives Rise to Innate-like B and T Cells. Cell Stem Cell. 2016 12 01; 19(6):768-783.
  11. Li Y, Phelps A, Zapala MA, MacKenzie JD, MacKenzie TC, Courtier J. Magnetic resonance imaging of Müllerian duct anomalies in children. Pediatr Radiol. 2016 May; 46(6):796-805.
  12. Frascoli M, Jeanty C, Fleck S, Moradi PW, Keating S, Mattis AN, Tang Q, MacKenzie TC. Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5. J Immunol. 2016 06 15; 196(12):4957-66.
  13. Derderian SC, Jayme CM, Cheng LS, Keller RL, Moon-Grady AJ, MacKenzie TC. Mass Effect Alone May Not Explain Pulmonary Vascular Pathology in Severe Congenital Diaphragmatic Hernia. Fetal Diagn Ther. 2016; 39(2):117-24.
  14. MacKenzie TC. Fetal Surgical conditions and the unraveling of maternal-fetal tolerance. J Pediatr Surg. 2016 Feb; 51(2):197-9.
  15. Walters MC, MacKenzie TC. A booster shot to cure hemoglobinopathies. Blood. 2015 Sep 03; 126(10):1159-61.
  16. Baer RJ, Chambers CD, Jones KL, Shew SB, MacKenzie TC, Shaw GM, Jelliffe-Pawlowski LL. Maternal factors associated with the occurrence of gastroschisis. Am J Med Genet A. 2015 Jul; 167(7):1534-41.
  17. Wegorzewska M, Le T, Tang Q, MacKenzie TC. Increased maternal T cell microchimerism in the allogeneic fetus during LPS-induced preterm labor in mice. Chimerism. 2014; 5(3-4):68-74.
  18. MacKenzie TC, David AL, Flake AW, Almeida-Porada G. Consensus statement from the first international conference for in utero stem cell transplantation and gene therapy. Front Pharmacol. 2015; 6:15.
  19. Derderian SC, Jeanty C, Walters MC, Vichinsky E, MacKenzie TC. In utero hematopoietic cell transplantation for hemoglobinopathies. Front Pharmacol. 2014; 5:278.
  20. Derderian SC, Moradi PW, MacKenzie TC. Placental drug delivery for treatment of congenital hematopoietic disorders. J Pediatr Surg. 2015 Sep; 50(9):1517-20.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.