Farzana Perwad, MD

Chief, Division of Nephrology

Dr. Farzana Perwad is a specialist who cares for children with kidney disease, including those requiring dialysis and kidney transplant. Her expertise includes evaluating and treating chronic kidney disease in children, nephrotic syndrome (a disorder that causes excessive excretion of protein in the urine), kidney stones, urinary tract infections, and kidney or urinary tract abnormalities that were present at birth. She also treats children with certain bone and mineral disorders, such as rickets and X-linked hypophosphatemia. In the UCSF Division of Nephrology, she serves as both division chief and director of the fellowship program.

Perwad earned her medical degree at Kasturba Medical College in India. She completed a residency in general pediatrics at Nicklaus Children's Hospital and a fellowship in pediatric nephrology at UCSF.

Perwad is a member of the American Society of Nephrology and American Society for Bone and Mineral Research.

Clinics

Kidney Transplant at Monterey
2 Upper Ragsdale Dr.
Monterey, CA
Phone: (415) 353-1551
Fax: (415) 353-8708

Kidney Transplant Program
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-8377
Toll-free: (800) 482-7389

Renal Center
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 476-2423

UCSF Pediatric Dialysis Unit
1825 Fourth St., Fifth Floor
San Francisco, CA 94158
Phone: (415) 353-2425
Fax: (415) 353-2768

More about Farzana Perwad

Education

Kasturba Medical College 1995

Residencies

Nicklaus Children's Hospital, Pediatrics 2001

Fellowships

UCSF, Pediatric Nephrology 2005

Selected Research and Publications

  1. Insogna KL, Briot K, Imel EA, Kamenický P, Ruppe MD, Portale AA, Weber T, Pitukcheewanont P, Cheong HI, Jan de Beur S, Imanishi Y, Ito N, Lachmann RH, Tanaka H, Perwad F, Zhang L, Chen CY, Theodore-Oklota C, Mealiffe M, San Martin J, Carpenter TO. A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial Evaluating the Efficacy of Burosumab, an Anti-FGF23 Antibody, in Adults With X-Linked Hypophosphatemia: Week 24 Primary Analysis. J Bone Miner Res. 2018 Jun 26.
  2. Cil O, Perwad F. Monogenic Causes of Proteinuria in Children. Front Med (Lausanne). 2018; 5:55.
  3. Portale AA, Wolf MS, Messinger S, Perwad F, Jüppner H, Warady BA, Furth SL, Salusky IB. Fibroblast Growth Factor 23 and Risk of CKD Progression in Children. Clin J Am Soc Nephrol. 2016 Nov 07; 11(11):1989-1998.
  4. Portale AA, Zhang MY, David V, Martin A, Jiao Y, Gu W, Perwad F. Characterization of FGF23-Dependent Egr-1 Cistrome in the Mouse Renal Proximal Tubule. PLoS One. 2015; 10(11):e0142924.
  5. Chanakul A, Zhang MY, Louw A, Armbrecht HJ, Miller WL, Portale AA, Perwad F. FGF-23 regulates CYP27B1 transcription in the kidney and in extra-renal tissues. PLoS One. 2013; 8(9):e72816.
  6. Zhang MY, Ranch D, Pereira RC, Armbrecht HJ, Portale AA, Perwad F. Chronic inhibition of ERK1/2 signaling improves disordered bone and mineral metabolism in hypophosphatemic (Hyp) mice. Endocrinology. 2012 Apr; 153(4):1806-16.
  7. Perwad F, Portale AA. Vitamin D metabolism in the kidney: regulation by phosphorus and fibroblast growth factor 23. Mol Cell Endocrinol. 2011 Dec 05; 347(1-2):17-24.
  8. Ranch D, Zhang MY, Portale AA, Perwad F. Fibroblast growth factor 23 regulates renal 1,25-dihydroxyvitamin D and phosphate metabolism via the MAP kinase signaling pathway in Hyp mice. J Bone Miner Res. 2011 Aug; 26(8):1883-90.
  9. Perwad F, Zhang MY, Tenenhouse HS, Portale AA. Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitro. Am J Physiol Renal Physiol. 2007 Nov; 293(5):F1577-83.
  10. Kim CJ, Kaplan LE, Perwad F, Huang N, Sharma A, Choi Y, Miller WL, Portale AA. Vitamin D 1alpha-hydroxylase gene mutations in patients with 1alpha-hydroxylase deficiency. J Clin Endocrinol Metab. 2007 Aug; 92(8):3177-82.
  11. Perwad F, Azam N, Zhang MY, Yamashita T, Tenenhouse HS, Portale AA. Dietary and serum phosphorus regulate fibroblast growth factor 23 expression and 1,25-dihydroxyvitamin D metabolism in mice. Endocrinology. 2005 Dec; 146(12):5358-64.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.