William Hoffman, MD

Chief of Plastic and Reconstructive Surgery
Plastic and reconstructive surgeon

Dr. William Hoffman is a plastic surgeon who specializes in treating children with a wide variety of craniofacial (skull or face) abnormalities, including cleft lip and cleft palate, craniosynostosis, facial palsy, and hemangiomas and other birthmarks or vascular anomalies. An innovator in the field of craniofacial and pediatric plastic surgery, he routinely performs complex and intricate surgeries, and works with orthodontists and other specialists to correct abnormalities in children's facial appearances while improving their breathing and ability to eat. He also treats adults, performing complex facial reconstructions as well as aesthetic facial surgeries, including facelifts, rhinoplasty (nose reshaping) and blepharoplasty (eyelid surgery). He is UCSF's chief of plastic and reconstructive surgery.

Hoffman is widely published, and his research interests include the biology of hemangiomas, fetal surgery for facial deformities and improving cleft lip surgery. Working with the California Society of Plastic Surgeons, Hoffman led a successful effort to pass legislation in California that greatly expands insurance coverage for children with cleft lip and palate. Hoffman has been named to U.S. News & World Report's list of America's best doctors for the past 15 years, a distinction reserved for the top 1 percent of physicians in the nation for a given specialty.

Hoffman earned his medical degree from the University of Rochester School of Medicine & Dentistry. At UCSF, he completed a residency in general surgery and a residency in plastic surgery, serving as chief resident. He then completed a fellowship in craniofacial and cleft lip surgery at NYU Langone Health.

Hoffman is treasurer of the California Society of Plastic Surgeons. He serves as a senior examiner for the American Board of Plastic Surgery and on its craniofacial surgery advisory council. He is past president of the American Association of Pediatric Plastic Surgeons and American Society of Maxillofacial Surgeons.

Clinics

Birthmarks and Vascular Anomalies Center
1825 Fourth St., Fifth Floor, 5B
San Francisco, CA 94158
Appointments: (415) 353-7823
Fax: (415) 353-7478

Craniofacial Center
1825 Fourth St., Fifth Floor, 5C
San Francisco, CA 94158
Phone: (415) 476-2271
Fax: (415) 476-9513

NF1 Clinic
1825 Fourth St., Fifth Floor
San Francisco, CA 94158
Phone: (855) PBC-UCSF
Fax: (415) 353-2400

Plastic and Reconstructive Surgery at Mission Bay
1825 Fourth St., Fifth Floor, 5B
San Francisco, CA 94158
Phone: (415) 353-4201
Fax: (415) 353-4330

Plastic and Reconstructive Surgery at Parnassus
400 Parnassus Ave., Sixth Floor, Suite A655
San Francisco, CA 94143-0932
Phone: (415) 353-4201
Fax: (415) 353-4330

Conditions & Treatments

More about William Hoffman

Education

University of Rochester School of Medicine 1977

Residencies

UCSF, General Surgery 1983
UCSF, Plastic Surgery 1985

Fellowships

New York University, Craniofacial Surgery 1986

Selected Research and Publications

  1. Garcia SM, Tamaki S, Lee S, Wong A, Jose A, Dreux J, Kouklis G, Sbitany H, Seth R, Knott PD, Heaton C, Ryan WR, Kim EA, Hansen SL, Hoffman WY, Pomerantz JH. High-Yield Purification, Preservation, and Serial Transplantation of Human Satellite Cells. Stem Cell Reports. 2018 Mar 13; 10(3):1160-1174.
  2. Daniels KM, Yang Yu E, Maine RG, Heng Y, Yang L, Shi B, Corlew DS, Hoffman WY, Gregory GA. Palatal Fistula Risk after Primary Palatoplasty: A Retrospective Comparison of a Humanitarian Organization and Tertiary Hospitals. Cleft Palate Craniofac J. 2018 Jan 01; 16007.
  3. Cho GJ, Wang F, Garcia SM, Viner J, Hoffman WY, McDermott MW, Pomerantz JH. Recalcitrant Invasive Skin Cancer of the Scalp: Combined Extirpation and Microsurgical Reconstruction Without Cranioplasty. J Craniofac Surg. 2017 Mar; 28(2):325-330.
  4. Piper ML, Delrosario L, Hoffman WY. Distraction Osteogenesis of Multiple Ribs for the Treatment of Acquired Thoracic Dystrophy. Pediatrics. 2016 Mar; 137(3):e20152053.
  5. Theiler M, Hoffman WY, Frieden IJ. Breast Hypoplasia as a Complication of an Untreated Infantile Hemangioma. Pediatr Dermatol. 2016 Mar-Apr; 33(2):e129-30.
  6. Xu X, Wilschut KJ, Kouklis G, Tian H, Hesse R, Garland C, Sbitany H, Hansen S, Seth R, Knott PD, Hoffman WY, Pomerantz JH. Human Satellite Cell Transplantation and Regeneration from Diverse Skeletal Muscles. Stem Cell Reports. 2015 Sep 08; 5(3):419-34.
  7. Koo KS, Dowd CF, Mathes EF, Rosbe KW, Hoffman WY, Frieden IJ, Hess CP. MRI phenotypes of localized intravascular coagulopathy in venous malformations. Pediatr Radiol. 2015 Oct; 45(11):1690-5.
  8. Patel AS, Schulman JM, Ruben BS, Hoffman WY, Dowd CF, Frieden IJ, Hess CP. Atypical MRI features in soft-tissue arteriovenous malformation: a novel imaging appearance with radiologic-pathologic correlation. Pediatr Radiol. 2015 Sep; 45(10):1515-21.
  9. Daniels KM, Yu EY, Maine RG, Corlew S, Bing S, Hoffman WY, Gregory GA. Palatal fistula risk after primary palatoplasty: a retrospective comparison of humanitarian operations and tertiary hospitals. Lancet. 2015 Apr 27; 385 Suppl 2:S37.
  10. Wang ED, Conkling N, Xu X, Chern H, Finlayson E, Varma MG, Hansen SL, Foster RD, Hoffman WY, Sbitany H. Perineal flap reconstruction following oncologic anorectal extirpation: an outcomes assessment. Plast Reconstr Surg. 2015 Jan; 135(1):176e-84e.
  11. Nguyen JT, Koerper MA, Hess CP, Dowd CF, Hoffman WY, Dickman M, Frieden IJ. Aspirin therapy in venous malformation: a retrospective cohort study of benefits, side effects, and patient experiences. Pediatr Dermatol. 2014 Sep-Oct; 31(5):556-60.
  12. Sbitany H, Xu X, Hansen SL, Young DM, Hoffman WY. The effects of immunosuppressive medications on outcomes in microvascular free tissue transfer. Plast Reconstr Surg. 2014 Apr; 133(4):552e-8e.
  13. Sanchez Rodriguez R, Pauli ML, Neuhaus IM, Yu SS, Arron ST, Harris HW, Yang SH, Anthony BA, Sverdrup FM, Krow-Lucal E, MacKenzie TC, Johnson DS, Meyer EH, Löhr A, Hsu A, Koo J, Liao W, Gupta R, Debbaneh MG, Butler D, Huynh M, Levin EC, Leon A, Hoffman WY, McGrath MH, Alvarado MD, Ludwig CH, Truong HA, Maurano MM, Gratz IK, Abbas AK, Rosenblum MD. Memory regulatory T cells reside in human skin. J Clin Invest. 2014 Mar; 124(3):1027-36.
  14. Vogel SA, Hess CP, Dowd CF, Hoffman WY, Kane AJ, Rajaii R, Frieden IJ. Early versus later presentations of venous malformations: where and why? Pediatr Dermatol. 2013 Sep-Oct; 30(5):534-40.
  15. Oberoi S, Hoffman WY, Chigurupati R, Vargervik K. Frequency of surgical correction for maxillary hypoplasia in cleft lip and palate. J Craniofac Surg. 2012 Nov; 23(6):1665-7.
  16. Oberoi S, Hoffman WY, Vargervik K. Craniofacial team management in Apert syndrome. Am J Orthod Dentofacial Orthop. 2012 Apr; 141(4 Suppl):S82-7.
  17. Ohtani J, Hoffman WY, Vargervik K, Oberoi S. Team management and treatment outcomes for patients with hemifacial microsomia. Am J Orthod Dentofacial Orthop. 2012 Apr; 141(4 Suppl):S74-81.
  18. Maine RG, Hoffman WY, Palacios-Martinez JH, Corlew DS, Gregory GA. Comparison of fistula rates after palatoplasty for international and local surgeons on surgical missions in Ecuador with rates at a craniofacial center in the United States. Plast Reconstr Surg. 2012 Feb; 129(2):319e-326e.
  19. Chang EI, Leon P, Hoffman WY, Schmidt BL. Quality of life for patients requiring surgical resection and reconstruction for mandibular osteoradionecrosis: 10-year experience at the University of California San Francisco. Head Neck. 2012 Feb; 34(2):207-12.
  20. Chang EI, Galvez MG, Padilla BE, Freise CE, Foster RD, Hoffman WY. Ten-year retrospective analysis of incisional herniorrhaphy following renal transplantation. Arch Surg. 2011 Jan; 146(1):21-5.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.