Walter E. B. Sipe, MD


Dr. Walter E. B. Sipe is a pediatrician with special training in gastroenterology. He cares for children with conditions that affect both the gut and the brain, such as chronic pain, as well as for children with dysautonomia (a category of conditions affecting the autonomic nervous system, which controls functions that occur without conscious effort). He provides supplementary counseling and support for effectively managing and coping with complex medical issues. He has also trained in psychiatry.

In his research, Sipe has examined gastrointestinal pain and hypersensitivity, as well as the use of mindfulness-based techniques for depression.

Sipe earned his medical degree from the University of California, San Diego. He completed a residency in pediatrics at Boston Children's Hospital and Boston Medical Center. At UCSF, he completed a fellowship in pediatric gastroenterology and a residency in psychiatry.

Sipe is a member of the American Neurogastroenterology and Motility Society, Association for Contextual Behavioral Science, International Society for Traumatic Stress Studies and American Medical Association.


Gastroenterology and Liver
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-2813
Fax: (415) 476-1343

More about Walter E. B. Sipe


UC San Diego School of Medicine 2001


Boston Children's Hospital and Boston Medical Center, Pediatrics 2004
UCSF, Psychiatry 2011


UCSF, Pediatric Gastroenterology 2008

Selected Research and Publications

  1. Eisendrath SJ, Gillung E, Delucchi K, Mathalon DH, Yang TT, Satre DD, Rosser R, Sipe WE, Wolkowitz OM. A Preliminary Study: Efficacy of Mindfulness-Based Cognitive Therapy versus Sertraline as First-line Treatments for Major Depressive Disorder. Mindfulness (N Y). 2015 Jun 01; 6(3):475-482.
  2. Sipe WE. Commentary on "psychotropic medications for pediatric functional gastrointestinal disorders". J Pediatr Gastroenterol Nutr. 2014 Sep; 59(3):279.
  3. Sipe WE, Eisendrath SJ. Mindfulness-based cognitive therapy: theory and practice. Can J Psychiatry. 2012 Feb; 57(2):63-9.
  4. Sipe WE, Brierley SM, Martin CM, Phillis BD, Cruz FB, Grady EF, Liedtke W, Cohen DM, Vanner S, Blackshaw LA, Bunnett NW. Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia. Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1288-98.
  5. Sipe WE, Rosenthal P. Autoimmune hepatitis in children: diagnosis, pathology and treatment. Expert Rev Clin Immunol. 2007 Mar; 3(2):159-69.
  6. Sipe WE, Su M, Posselt A, Kim GE, Quiros JA, Rosenthal P. Propylthiouracil-associated liver failure presenting as probable autoimmune hepatitis in a child with Graves' disease. Pediatr Transplant. 2006 Jun; 10(4):525-8.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.