Shylaja Srinivasan, MD

Pediatric endocrinologist

Dr. Shylaja Srinivasan is a pediatric endocrinologist who treats children with endocrine conditions related to growth, puberty, thyroid or adrenal disorders, and bone and calcium disorders, as well as type 1 and type 2 diabetes. Srinivasan has a special interest in youth-onset type 2 diabetes, an increasingly common condition caused by a complex interplay between genetics and environment.

Srinivasan's research focuses on understanding the genes behind type 2 diabetes in adults and children. Her research also explores the genetic basis for different responses to diabetes medications, particularly metformin.

Srinivasan is originally from Chennai in South India and earned her medical degree from the Pondicherry Institute of Medical Sciences. She then completed residencies in pediatrics at SUNY Downstate Medical Center and Tufts Medical Center as well as a Harvard Medical School fellowship in pediatric endocrinology at Massachusetts General Hospital.

Srinivasan received the 2016 Pediatric Endocrine Society's Clinical Scholar Award, a grant to pursue research in type 2 diabetes genetics. She is a clinical instructor of pediatrics at UCSF and a member of the Pediatric Endocrine Society, Endocrine Society, American Diabetes Association and American Society of Human Genetics.


Endocrinology Clinic
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-7337
Fax: (415) 476-8214

Madison Clinic for Pediatric Diabetes
1500 Owens St., Suite 300
San Francisco, CA 94158
Phone: (415) 514-6234
Fax: (415) 353-2811

More about Shylaja Srinivasan

Additional Languages



Pondicherry Institute of Medical Sciences and Research 2008


SUNY Downstate Medical Center , Pediatrics 2012
Tufts Medical Center, Pediatrics 2013


Massachusetts General Hospital , Pediatric endocrinology 2016

Selected Research and Publications

  1. Srinivasan S, Kaur V, Chamarthi B, Littleton KR, Chen L, Manning AK, Merino J, Thomas MK, Hudson M, Goldfine A, Florez JC. TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH). Diabetes Care. 2018 Mar; 41(3):554-561.
  2. Srinivasan S, O'Rourke J, Bersche Golas S, Neumeyer A, Misra M. Calcium and Vitamin D Supplement Prescribing Practices among Providers Caring for Children with Autism Spectrum Disorders: Are We Addressing Bone Health? Autism Res Treat. 2016; 2016:6763205.
  3. Srinivasan S, Florez JC. Therapeutic Challenges in Diabetes Prevention: We Have Not Found the "Exercise Pill". Clin Pharmacol Ther. 2015 Aug; 98(2):162-9.
  4. Srinivasan S, Misra M. Hyperthyroidism in children. Pediatr Rev. 2015 Jun; 36(6):239-48.
  5. Kaplowitz P, Srinivasan S, He J, McCarter R, Hayeri MR, Sze R. Comparison of bone age readings by pediatric endocrinologists and pediatric radiologists using two bone age atlases. Pediatr Radiol. 2011 Jun; 41(6):690-3.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.