Ilona Frieden, MD

Division Chief, Pediatric Dermatology at UCSF Benioff Children's Hospital

Dr. Ilona Frieden, a world-renowned specialist in children's skin diseases, is director of Pediatric Dermatology at UCSF Benioff Children's Hospital. She has more than 35 years of experience caring for children with skin conditions that range from eczema and diaper rash to rare genetic disorders and those occurring within complex disease syndromes.

Frieden also cares for children with birthmarks and has a special interest in those that arise from abnormal blood vessels, including hemangiomas and vascular malformations. She directs the UCSF Birthmarks & Vascular Anomalies Center, which she helped found in 1991.

Frieden earned her medical degree at UCSF, where she also completed residencies in pediatrics and dermatology. For more than 12 years, she has served as an editor-in-chief of the journal Pediatric Dermatology. She is co-editor of the textbook Neonatal and Infant Dermatology, now in its third edition. She has authored and co-authored dozens of book chapters and more than 250 peer-reviewed articles.

Freiden is a member of the American Academy of Dermatology, American Academy of Pediatrics, Society for Pediatric Dermatology, American Dermatological Association, Women's Dermatologic Association and International Society for the Study of Vascular Anomalies.


Birthmarks and Vascular Anomalies Center
1825 Fourth St., Fifth Floor, 5B
San Francisco, CA 94158
Appointments: (415) 353-7823
Clinic: (415) 353-7800
Fax: (415) 353-7478

Craniofacial Center
1825 Fourth St., Fifth Floor, 5C
San Francisco, CA 94158
Phone: (415) 476-2271
Fax: (415) 476-9513

Dermatology at Mission Bay
1825 Fourth St., Fifth Floor, 5B
San Francisco, CA 94158
Phone: (415) 353-7800
Fax: (415) 353-7870

Dermatology at Mount Zion
1701 Divisadero St., Third Floor
San Francisco, CA 94143-0316
Phone: (415) 353-7800
Fax: (415) 353-7870

HHT Center of Excellence
1825 Fourth St., Fifth Floor, 5A
San Francisco, CA 94158
Phone: (415) 353-8867
Fax: (415) 353-3158

Conditions & Treatments

More about Ilona Frieden

Additional Languages



UCSF 1977


UCSF, Pediatrics 1980


UCSF, Dermatology 1983

Selected Research and Publications

  1. Horbach SER, van der Horst CMAM, Blei F, van der Vleuten CJM, Frieden IJ, Richter GT, Tan ST, Muir T, Penington AJ, Boon LM, Spuls PI. Development of an international core outcome set for peripheral vascular malformations: the OVAMA project. Br J Dermatol. 2018 Feb; 178(2):473-481.
  2. Frieden IJ, Eichenfield LF. A Note from the Journal's Editors-in-Chief. Pediatr Dermatol. 2018 01; 35(1):7.
  3. Walsh R, North J, Cordoro KM, Rodríguez Bandera AI, Kristal L, Frieden IJ. Midline anterior neck inclusion cyst: A novel superficial congenital developmental anomaly of the neck. Pediatr Dermatol. 2018 Jan; 35(1):55-58.
  4. Siegel DH, Cottrell CE, Streicher JL, Schilter KF, Basel DG, Baselga E, Burrows PE, Ciliberto HM, Vigh-Conrad KA, Eichenfield LF, Holland KE, Hogeling M, Jensen JN, Kelly ME, Kim W, King DM, McCuaig C, Mueller KA, Pope E, Powell J, Price H, Steiner JE, Frieden IJ, Tollefson MM, Drolet BA. Analyzing the Genetic Spectrum of Vascular Anomalies with Overgrowth via Cancer Genomics. J Invest Dermatol. 2018 Apr; 138(4):957-967.
  5. Theiler M, Baselga E, Gerth-Kahlert C, Mathes EF, Schwieger-Briel A, Chaloupka K, Weibel L, Frieden IJ. Infantile hemangiomas with conjunctival involvement: An underreported occurrence. Pediatr Dermatol. 2017 Nov; 34(6):681-685.
  6. Wan J, Steiner J, Baselga E, Blei F, Cordisco M, Garzon MC, Goddard DS, Haggstrom A, Krol A, Frieden IJ, Metry D, Morel KD, Verhagen JMA, Wargon O, Drolet BA, Siegel DH. Prenatal Risk Factors for PHACE Syndrome: A Study Using the PHACE Syndrome International Clinical Registry and Genetic Repository. J Pediatr. 2017 Nov; 190:275-279.
  7. Planas-Ciudad S, Roé Crespo E, Sánchez-Carpintero I, Frieden IJ, Martín-Santiago A, Redondo Bellón P, Moreno Artero E, Osier E, Puig Sanz L, Baselga Torres E. Infantile hemangiomas with minimal or arrested growth associated with soft tissue hypertrophy: a case series of 10 patients. J Eur Acad Dermatol Venereol. 2017 Nov; 31(11):1924-1929.
  8. Feigenbaum DF, Boscardin CK, Frieden IJ, Mathes EFD. Can You See Me Now? Video Supplementation for Pediatric Teledermatology Cases. Pediatr Dermatol. 2017 Sep; 34(5):566-571.
  9. Amyere M, Revencu N, Helaers R, Pairet E, Baselga E, Cordisco M, Chung W, Dubois J, Lacour JP, Martorell L, Mazereeuw-Hautier J, Pyeritz RE, Amor DJ, Bisdorff A, Blei F, Bombei H, Dompmartin A, Brooks D, Dupont J, González-Enseñat MA, Frieden I, Gérard M, Kvarnung M, Hanson-Kahn AK, Hudgins L, Léauté-Labrèze C, McCuaig C, Metry D, Parent P, Paul C, Petit F, Phan A, Quere I, Salhi A, Turner A, Vabres P, Vicente A, Wargon O, Watanabe S, Weibel L, Wilson A, Willing M, Mulliken JB, Boon LM, Vikkula M. Germline Loss-of-Function Mutations in EPHB4 Cause a Second Form of Capillary Malformation-Arteriovenous Malformation (CM-AVM2) Deregulating RAS-MAPK Signaling. Circulation. 2017 Sep 12; 136(11):1037-1048.
  10. Mamlouk MD, Maheshwari M, Burrows PE, Siegel DH, Frieden IJ, Drolet BA, Hess CP. PHACE syndrome and cerebral cavernous malformations: association or simply microhemorrhages? Childs Nerv Syst. 2017 Sep; 33(9):1421-1422.
  11. Frieden IJ, Eichenfield LF. A Note from the Editors. Pediatr Dermatol. 2017 May; 34(3):228.
  12. Durr ML, Meyer AK, Kezirian EJ, Mamlouk MD, Frieden IJ, Rosbe KW. Sleep-disordered breathing in pediatric head and neck vascular malformations. Laryngoscope. 2017 Sep; 127(9):2159-2164.
  13. Garzon MC, Epstein LG, Heyer GL, Frommelt PC, Orbach DB, Baylis AL, Blei F, Burrows PE, Chamlin SL, Chun RH, Hess CP, Joachim S, Johnson K, Kim W, Liang MG, Maheshwari M, McCoy GN, Metry DW, Monrad PA, Pope E, Powell J, Shwayder TA, Siegel DH, Tollefson MM, Vadivelu S, Lew SM, Frieden IJ, Drolet BA. PHACE Syndrome: Consensus-Derived Diagnosis and Care Recommendations. J Pediatr. 2016 Nov; 178:24-33.e2.
  14. Luu M, Frieden IJ. Infantile hemangiomas and structural anomalies: PHACE and LUMBAR syndrome. Semin Cutan Med Surg. 2016 Sep; 35(3):117-23.
  15. Püttgen K, Lucky A, Adams D, Pope E, McCuaig C, Powell J, Feigenbaum D, Savva Y, Baselga E, Holland K, Drolet B, Siegel D, Morel KD, Garzon MC, Mathes E, Lauren C, Nopper A, Horii K, Newell B, Song W, Frieden I. Topical Timolol Maleate Treatment of Infantile Hemangiomas. Pediatrics. 2016 Sep; 138(3).
  16. Rozas-Muñoz E, Frieden IJ, Roé E, Puig L, Baselga E. Vascular Stains: Proposal for a Clinical Classification to Improve Diagnosis and Management. Pediatr Dermatol. 2016 Nov; 33(6):570-584.
  17. Brosig CL, Siegel DH, Haggstrom AN, Frieden IJ, Drolet BA. Neurodevelopmental Outcomes in Children with PHACE Syndrome. Pediatr Dermatol. 2016 Jul; 33(4):415-23.
  18. Hanifin JM, Ellis CN, Frieden IJ, Fölster-Holst R, Stein Gold LF, Secci A, Smith AJ, Zhao C, Kornyeyeva E, Eichenfield LF. OPA-15406, a novel, topical, nonsteroidal, selective phosphodiesterase-4 (PDE4) inhibitor, in the treatment of adult and adolescent patients with mild to moderate atopic dermatitis (AD): A phase-II randomized, double-blind, placebo-controlled study. J Am Acad Dermatol. 2016 Aug; 75(2):297-305.
  19. Noguera-Morel L, Stein SL, Xirotagaros G, Hernández-Martín A, de Prada I, Frieden IJ, Requena L, Torrelo A. Net-like superficial vascular malformation: clinical description and evidence for lymphatic origin. Br J Dermatol. 2016 Jul; 175(1):191-3.
  20. Oza VS, Feigenbaum DF, Jacquot C, Hess CP, Siegel D, Frieden IJ. Fetal Alcohol Exposure and PHACE Syndrome: A Case and Autopsy Report. Pediatr Dermatol. 2016 May; 33(3):e179-e183.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.