Ilona Frieden, MD

Director of Pediatric Dermatology

Dr. Ilona Frieden, director of Pediatric Dermatology at UCSF Benioff Children's Hospital, is a world-renowned specialist in children's skin diseases. She has more than 30 years experience in treating conditions including birthmarks and hemangiomas, laser surgery of port-wine stains and in caring for children with common conditions such as eczema and rashes. She is founder and director of the UCSF Birthmarks and Vascular Anomalies Clinic founded in 1991 and treats patients in the Ectodermal Dysplasia Clinic of the Craniofacial Anomalies Center.

Frieden is a clinical professor of dermatology and pediatrics and the founder of the Hemangioma Investigator Group, a multi-center collaboration for the study of hemangiomas. She is the editor in chief of the journal Pediatric Dermatology. She is also a member of the board of the American Academy of Dermatology.


Birthmarks and Vascular Anomalies Center
1825 Fourth St., Fifth Floor, 5B
San Francisco, CA 94158
Appointments: (415) 353-7823
Clinic: (415) 353-7800
Fax: (415) 353-7478

Craniofacial Center
1825 Fourth St., Fifth Floor, 5C
San Francisco, CA 94158
Phone: (415) 476-2271
Fax: (415) 476-9513

Dermatology at Mission Bay
1825 Fourth St., Fifth Floor, 5B
San Francisco, CA 94158
Phone: (415) 353-7800
Fax: (415) 353-7870

Dermatology at Mount Zion
1701 Divisadero St., Third Floor
San Francisco, CA 94143-0316
Phone: (415) 353-7800
Fax: (415) 353-7870

HHT Center of Excellence
1825 Fourth St., Fifth Floor, 5A
San Francisco, CA 94158
Phone: (415) 353-8867
Fax: (415) 353-3158

Conditions & Treatments

More about Ilona Frieden

Additional Languages



UCSF School of Medicine 1977


UCSF Medical Center, Pediatrics 1980


UCSF Medical Center, Dermatology 1983

Selected Research and Publications

  1. Wan J, Steiner J, Baselga E, Blei F, Cordisco M, Garzon MC, Goddard DS, Haggstrom A, Krol A, Frieden IJ, Metry D, Morel KD, Verhagen JMA, Wargon O, Drolet BA, Siegel DH. Prenatal Risk Factors for PHACE Syndrome: A Study Using the PHACE Syndrome International Clinical Registry and Genetic Repository. J Pediatr. 2017 Aug 31.
  2. Feigenbaum DF, Boscardin CK, Frieden IJ, Mathes EFD. Can You See Me Now? Video Supplementation for Pediatric Teledermatology Cases. Pediatr Dermatol. 2017 Sep; 34(5):566-571.
  3. Amyere M, Revencu N, Helaers R, Pairet E, Baselga E, Cordisco M, Chung W, Dubois J, Lacour JP, Martorell L, Mazereeuw-Hautier J, Pyeritz RE, Amor DJ, Bisdorff A, Blei F, Bombei H, Dompmartin A, Brooks D, Dupont J, González-Enseñat MA, Frieden I, Gérard M, Kvarnung M, Hanson-Kahn AK, Hudgins L, Léauté-Labrèze C, McCuaig C, Metry D, Parent P, Paul C, Petit F, Phan A, Quere I, Salhi A, Turner A, Vabres P, Vicente A, Wargon O, Watanabe S, Weibel L, Wilson A, Willing M, Mulliken JB, Boon LM, Vikkula M. Germline Loss-of-Function Mutations in EPHB4 Cause a Second Form of Capillary Malformation-Arteriovenous Malformation (CM-AVM2) Deregulating RAS-MAPK Signaling. Circulation. 2017 Sep 12; 136(11):1037-1048.
  4. Planas-Ciudad S, Roé Crespo E, Sánchez-Carpintero I, Frieden IJ, Martín-Santiago A, Redondo Bellón P, Moreno Artero E, Osier E, Puig Sanz L, Baselga Torres E. Infantile hemangiomas with minimal or arrested growth associated with soft tissue hypertrophy: a case series of 10 patients. J Eur Acad Dermatol Venereol. 2017 Jul 05.
  5. Mamlouk MD, Maheshwari M, Burrows PE, Siegel DH, Frieden IJ, Drolet BA, Hess CP. PHACE syndrome and cerebral cavernous malformations: association or simply microhemorrhages? Childs Nerv Syst. 2017 Jun 16.
  6. Frieden IJ, Eichenfield LF. A Note from the Editors. Pediatr Dermatol. 2017 May; 34(3):228.
  7. Durr ML, Meyer AK, Kezirian EJ, Mamlouk MD, Frieden IJ, Rosbe KW. Sleep-disordered breathing in pediatric head and neck vascular malformations. Laryngoscope. 2017 Sep; 127(9):2159-2164.
  8. Garzon MC, Epstein LG, Heyer GL, Frommelt PC, Orbach DB, Baylis AL, Blei F, Burrows PE, Chamlin SL, Chun RH, Hess CP, Joachim S, Johnson K, Kim W, Liang MG, Maheshwari M, McCoy GN, Metry DW, Monrad PA, Pope E, Powell J, Shwayder TA, Siegel DH, Tollefson MM, Vadivelu S, Lew SM, Frieden IJ, Drolet BA. PHACE Syndrome: Consensus-Derived Diagnosis and Care Recommendations. J Pediatr. 2016 Nov; 178:24-33.e2.
  9. Luu M, Frieden IJ. Infantile hemangiomas and structural anomalies: PHACE and LUMBAR syndrome. Semin Cutan Med Surg. 2016 Sep; 35(3):117-23.
  10. Püttgen K, Lucky A, Adams D, Pope E, McCuaig C, Powell J, Feigenbaum D, Savva Y, Baselga E, Holland K, Drolet B, Siegel D, Morel KD, Garzon MC, Mathes E, Lauren C, Nopper A, Horii K, Newell B, Song W, Frieden I. Topical Timolol Maleate Treatment of Infantile Hemangiomas. Pediatrics. 2016 Sep; 138(3).
  11. Rozas-Muñoz E, Frieden IJ, Roé E, Puig L, Baselga E. Vascular Stains: Proposal for a Clinical Classification to Improve Diagnosis and Management. Pediatr Dermatol. 2016 Nov; 33(6):570-584.
  12. Brosig CL, Siegel DH, Haggstrom AN, Frieden IJ, Drolet BA. Neurodevelopmental Outcomes in Children with PHACE Syndrome. Pediatr Dermatol. 2016 Jul; 33(4):415-23.
  13. Hanifin JM, Ellis CN, Frieden IJ, Fölster-Holst R, Stein Gold LF, Secci A, Smith AJ, Zhao C, Kornyeyeva E, Eichenfield LF. OPA-15406, a novel, topical, nonsteroidal, selective phosphodiesterase-4 (PDE4) inhibitor, in the treatment of adult and adolescent patients with mild to moderate atopic dermatitis (AD): A phase-II randomized, double-blind, placebo-controlled study. J Am Acad Dermatol. 2016 Aug; 75(2):297-305.
  14. Noguera-Morel L, Stein SL, Xirotagaros G, Hernández-Martín A, de Prada I, Frieden IJ, Requena L, Torrelo A. Net-like superficial vascular malformation: clinical description and evidence for lymphatic origin. Br J Dermatol. 2016 Jul; 175(1):191-3.
  15. Oza VS, Feigenbaum DF, Jacquot C, Hess CP, Siegel D, Frieden IJ. Fetal Alcohol Exposure and PHACE Syndrome: A Case and Autopsy Report. Pediatr Dermatol. 2016 May; 33(3):e179-e183.
  16. Shah SD, Baselga E, McCuaig C, Pope E, Coulie J, Boon LM, Garzon MC, Haggstrom AN, Adams D, Drolet BA, Newell BD, Powell J, García-Romero MT, Chute C, Roe E, Siegel DH, Grimes B, Frieden IJ. Rebound Growth of Infantile Hemangiomas After Propranolol Therapy. Pediatrics. 2016 Apr; 137(4).
  17. Greco MF, Frieden IJ, Drolet BA, Garzon MC, Mancini AJ, Chamlin SL, Metry D, Adams D, Lucky A, Wentzel MS, Horii KA, Baselga E, McCuaig CC, Powell J, Haggstrom A, Siegel D, Morel KD, Cordisco MR, Nopper AJ, Krol A. Infantile Hemangiomas in Twins: A Prospective Cohort Study. Pediatr Dermatol. 2016 Mar-Apr; 33(2):178-83.
  18. Oza VS, Mamlouk MD, Hess CP, Mathes EF, Frieden IJ. Role of Sirolimus in Advanced Kaposiform Hemangioendothelioma. Pediatr Dermatol. 2016 Mar-Apr; 33(2):e88-92.
  19. Theiler M, Frieden IJ. High-Potency Topical Steroids: An Effective Therapy for Chronic Scalp Inflammation in Rapp-Hodgkin Ectodermal Dysplasia. Pediatr Dermatol. 2016 Mar-Apr; 33(2):e84-7.
  20. Frieden I, Eichenfield L. Walter (Wally) Burgdorf, M.D., 1943-2015. Pediatr Dermatol. 2016 Mar-Apr; 33(2):243.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.