Daniel Cooke, MD

Neurointerventional radiologist

Dr. Daniel Cooke is a neurointerventional radiologist – a specialist in the use of imaging technologies and endovascular surgery – who cares for adults and children with stroke and other vascular disorders. He has a special focus on brain aneurysms and arteriovenous malformations (AVMs), atherosclerosis (the buildup of fatty substances in arteries) and vascular anomalies.

Cooke is chief of neurointerventional radiology at Zuckerberg San Francisco General Hospital and Trauma Center and at the San Francisco Veterans Affairs Medical Center.

Cooke's research focuses on the genetics and medical management of brain and spine vascular disorders, including aneurysms, AVMs, arteriovenous fistulas (abnormal connections between arteries and veins) and atherosclerosis. Along with Dr. Zhengda Sun, he has pioneered methods for collecting cells from inside arteries and veins, facilitating genetic analysis of single cells. These efforts enhance understanding of potential causes of vascular diseases and can help the medical community develop new treatments for patients with limited conventional options as well as nonsurgical alternatives for those who might have otherwise undergone an operation.

Cooke earned his medical degree at Emory University School of Medicine, where he graduated as a member of the Alpha Omega Alpha Honor Medical Society. He completed a residency in radiology and a fellowship in neuroradiology at the University of Washington, followed by a fellowship in neurointerventional radiology at UCSF.

Cooke is a member of the American Heart Association, American Stroke Association, Society of NeuroInterventional Surgery, American Society of Neuroradiology and Radiological Society of North America.

Cooke is involved in efforts to bring advanced medical imaging tools to regions of the developing world. He is a member of the education initiative Health4TheWorld as well as a supporter of the work done by Dr. Melanie Walker of the University of Washington, who promotes excellence in neurointerventional practices overseas.

Clinics

Birthmarks and Vascular Anomalies Center
1825 Fourth St., Fifth Floor, 5B
San Francisco, CA 94158
Appointments: (415) 353-7823
Fax: (415) 353-7478

HHT Center of Excellence
1825 Fourth St., Fifth Floor, 5A
San Francisco, CA 94158
Phone: (415) 353-8867
Fax: (415) 353-3158

Neurointerventional Radiology
1825 Fourth St., Fifth Floor
San Francisco, CA 94158
Consultation: (415) 353-1863
Schedule a Procedure: (415) 353-1869
Fax: (415) 353-8606

Conditions & Treatments

More about Daniel Cooke

Education

Emory University School of Medicine 2004

Residencies

University of Washington, Radiology 2010

Fellowships

University of Washington, Neuroradiology 2010
UCSF, Neurointerventional Radiology 2012

Selected Research and Publications

  1. Talbott JF, Cooke DL, Mabray MC, Larson PS, Amans MR, Hetts SW, Wilson MW, Moore T, Salegio EA. Accuracy of image-guided percutaneous injection into a phantom spinal cord utilizing flat panel detector CT with MR fusion and integrated navigational software. J Neurointerv Surg. 2018 Apr 17.
  2. LaHue SC, Kim H, Pawlikowska L, Nelson J, Cooke DL, Hetts SW, Singh V. Frequency and characteristics associated with inherited thrombophilia in patients with intracranial dural arteriovenous fistula. J Neurosurg. 2018 Apr 06; 1-5.
  3. Morrison J, Alexander MD, Dowd CF, Cooke DL. Flanking the fenestration: circumferential limb-to-limb stent-assisted coiling of a basilar artery fenestration aneurysm. J Neurointerv Surg. 2018 Mar 21.
  4. Yen AJ, Conrad MB, Loftus PA, Kumar V, Nanavati SM, Wilson MW, Cooke DL. Internal Jugular Vein Embolization to Control Life-Threatening Hemorrhage after Penetrating Neck Trauma. J Vasc Interv Radiol. 2018 Mar; 29(3):435-437.
  5. Alexander MD, Hippe DS, Cooke DL, Hallam DK, Hetts SW, Kim H, Lawton MT, Sekhar LN, Kim LJ, Ghodke BV. Targeted Embolization of Aneurysms Associated With Brain Arteriovenous Malformations at High Risk for Surgical Resection: A Case-Control Study. Neurosurgery. 2018 Mar 01; 82(3):343-349.
  6. Kondapavulur S, Cooke DL, Kao A, Amans MR, Alexander M, Darflinger R, Dowd CF, Higashida RT, Damato B, Halbach VV, Matthay KK, Hetts SW. Estimation of intra-arterial chemotherapy distribution to the retina in pediatric retinoblastoma patients using quantitative digital subtraction angiography. Interv Neuroradiol. 2018 Apr; 24(2):214-219.
  7. Yu JF, Nicholson AD, Nelson J, Alexander MD, Tse SH, Hetts SW, Hemphill JC, Kim H, Cooke DL. Predictors of intracranial hemorrhage volume and distribution in brain arteriovenous malformation. Interv Neuroradiol. 2018 Apr; 24(2):183-188.
  8. Ammanuel S, Alexander MD, Damato B, Cooke DL, Halbach VV, Amans MR, Dowd CF, Higashida RT, Hetts SW. Improved procedural safety following protocol changes for selective ophthalmic arterial infusion of chemotherapy for treatment of ocular retinoblastoma. Interv Neuroradiol. 2018 Jan 01; 1591019918755088.
  9. Hirabayashi KE, Kalin-Hajdu E, Bever GJ, Vagefi MR, de Alba Campomanes AG, Cooke DL, Dowd CF, Kersten RC. Normalization of Congenital Venous Stasis Retinopathy Following Sclerotherapy of a Macrocystic Lymphatic Malformation. Ophthal Plast Reconstr Surg. 2018 Jan/Feb; 34(1):e19-e21.
  10. Sun Z, Wang CY, Lawson DA, Kwek S, Velozo HG, Owyong M, Lai MD, Fong L, Wilson M, Su H, Werb Z, Cooke DL. Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells. Oncotarget. 2018 Feb 16; 9(13):10945-10961.
  11. Alexander MD, Rebhun JM, Hetts SW, Amans MR, Settecase F, Darflinger RJ, Dowd CF, Halbach VV, Higashida RT, Cooke DL. Technical factors affecting outcomes following endovascular treatment of posterior circulation atherosclerotic lesions. Surg Neurol Int. 2017; 8:284.
  12. Settecase F, McCoy DB, Darflinger R, Alexander MD, Cooke DL, Dowd CF, Hetts SW, Higashida RT, Halbach VV, Amans MR. Improving mechanical thrombectomy time metrics in the angiography suite: Stroke cart, parallel workflows, and conscious sedation. Interv Neuroradiol. 2018 Apr; 24(2):168-177.
  13. Morrison J, Alexander MD, Dowd CF, Cooke DL. Flanking the fenestration: circumferential limb-to-limb stent-assisted coiling of a basilar artery fenestration aneurysm. BMJ Case Rep. 2017 Oct 13; 2017.
  14. Burkhardt JK, Chen X, Winkler EA, Weiss M, Yue JK, Cooke DL, Kim H, Lawton MT. Early Hemodynamic Changes Based on Initial Color-Coding Angiography as a Predictor for Developing Subsequent Symptomatic Vasospasm After Aneurysmal Subarachnoid Hemorrhage. World Neurosurg. 2018 Jan; 109:e363-e373.
  15. Yang JK, Cote AM, Jordan CD, Kondapavulur S, Losey AD, McCoy D, Chu A, Yu JF, Moore T, Stillson C, Settecase F, Alexander MD, Nicholson A, Cooke DL, Saeed M, Barry D, Martin AJ, Wilson MW, Hetts SW. Interventional magnetic resonance imaging guided carotid embolectomy using a novel resonant marker catheter: demonstration of preclinical feasibility. Biomed Microdevices. 2017 Sep 25; 19(4):88.
  16. Cooke DL, McCoy DB, Halbach VV, Hetts SW, Amans MR, Dowd CF, Higashida RT, Lawson D, Nelson J, Wang CY, Kim H, Werb Z, McCulloch C, Hashimoto T, Su H, Sun Z. Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis. Transl Stroke Res. 2018 Feb; 9(1):20-33.
  17. Chen X, Cooke DL, Saloner D, Nelson J, Su H, Lawton MT, Hess C, Tihan T, Zhao Y, Kim H. Higher Flow Is Present in Unruptured Arteriovenous Malformations With Silent Intralesional Microhemorrhages. Stroke. 2017 10; 48(10):2881-2884.
  18. Mamlouk MD, Nicholson AD, Cooke DL, Hess CP. Diffusion-weighted imaging for cutaneous vascular anomalies. Clin Imaging. 2017 Nov - Dec; 46:121-122.
  19. Derdeyn CP, Zipfel GJ, Albuquerque FC, Cooke DL, Feldmann E, Sheehan JP, Torner JC. Management of Brain Arteriovenous Malformations: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2017 08; 48(8):e200-e224.
  20. Mamlouk MD, Nicholson AD, Cooke DL, Hess CP. Tips and tricks to optimize MRI protocols for cutaneous vascular anomalies. Clin Imaging. 2017 Sep - Oct; 45:71-80.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.