Andrew Posselt, MD, PhD

Bariatric and transplant surgeon

Dr. Andrew Posselt, a bariatric and transplant surgeon, is co-director of the Pancreatic Islet Transplantation Program at UCSF Medical Center. He specializes in adult and pediatric kidney, liver and pancreas transplantation, as well as laparoscopic and open (traditional) bariatric surgery.

In addition to caring for patients, Posselt conducts research on pancreatic islet cell transplantation, a procedure that can allow people with type 1 diabetes to discontinue insulin therapy. He also investigates mechanisms by which a transplant recipient's body rejects or tolerates tissue from a donor who isn't genetically identical, and he studies the metabolic and biochemical consequences of bariatric surgery.

Posselt earned his medical degree and a doctorate in immunology from the University of Pennsylvania. He completed residencies in internal medicine and general surgery as well as a transplant fellowship at UCSF, before joining the staff in 2003.

Posselt is a member of several professional and honorary societies, and has given presentations on transplant issues related to patient care and research. At UCSF, he supervises residents and fellows in transplant services and general surgery.

Read a Q&A with Posselt, who discusses islet cell transplants to treat diabetes.

Clinics

Kidney Transplant Program
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-8377
Toll-free: (800) 482-7389

Liver Transplant Program
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 476-5892
Fax: (415) 476-1343

Pancreas Program
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-2813
Fax: (415) 476-1343

Conditions & Treatments

More about Andrew Posselt

Additional Languages

Czechoslovakian
French
German
Spanish

Education

University of Pennsylvania School of Medicine 1993

Residencies

UCSF Medical Center, Internal Medicine 1996
UCSF Medical Center, Surgery 2000

Selected Research and Publications

  1. Schafer AL, Kazakia GJ, Vittinghoff E, Stewart L, Rogers SJ, Kim TY, Carter JT, Posselt AM, Pasco C, Shoback DM, Black DM. Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture Occur Early and Particularly Impact Postmenopausal Women. J Bone Miner Res. 2017 Dec 27.
  2. Kim TY, Schwartz AV, Li X, Xu K, Black DM, Petrenko DM, Stewart L, Rogers SJ, Posselt AM, Carter JT, Shoback DM, Schafer AL. Bone Marrow Fat Changes After Gastric Bypass Surgery Are Associated With Loss of Bone Mass. J Bone Miner Res. 2017 Nov; 32(11):2239-2247.
  3. Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AMJ. Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428. Diabetes. 2017 09; 66(9):2531.
  4. Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S. Correction: An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport. Lab Chip. 2017 06 27; 17(13):2334.
  5. Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S. An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport. Lab Chip. 2017 05 16; 17(10):1778-1792.
  6. Song S, Yeung R, Park J, Posselt AM, Desai TA, Tang Q, Roy S. Glucose-Stimulated Insulin Response of Silicon Nanopore-Immunoprotected Islets under Convective Transport. ACS Biomater Sci Eng. 2017 Jun 12; 3(6):1051-1061.
  7. Yamanaga S, Posselt AM, Freise CE, Kobayashi T, Tavakol M, Kang SM. A Single Perioperative Injection of Dexamethasone Decreases Nausea, Vomiting, and Pain after Laparoscopic Donor Nephrectomy. J Transplant. 2017; 2017:3518103.
  8. Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Chen X, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AM, Chen X. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes. 2016 11; 65(11):3418-3428.
  9. Kasiske BL, Kumar R, Kimmel PL, Pesavento TE, Kalil RS, Kraus ES, Rabb H, Posselt AM, Anderson-Haag TL, Steffes MW, Israni AK, Snyder JJ, Singh RJ, Weir MR. Abnormalities in biomarkers of mineral and bone metabolism in kidney donors. Kidney Int. 2016 10; 90(4):861-8.
  10. Hering BJ, Clarke WR, Bridges ND, Eggerman TL, Alejandro R, Bellin MD, Chaloner K, Czarniecki CW, Goldstein JS, Hunsicker LG, Kaufman DB, Korsgren O, Larsen CP, Luo X, Markmann JF, Naji A, Oberholzer J, Posselt AM, Rickels MR, Ricordi C, Robien MA, Senior PA, Shapiro AM, Stock PG, Turgeon NA. Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia. Diabetes Care. 2016 07; 39(7):1230-40.
  11. Song S, Faleo G, Yeung R, Kant R, Posselt AM, Desai TA, Tang Q, Roy S. Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport. Sci Rep. 2016 Mar 24; 6:23679.
  12. Wang LJ, Kin T, O'Gorman D, Shapiro AMJ, Naziruddin B, Takita M, Levy MF, Posselt AM, Szot GL, Savari O, Barbaro B, McGarrigle J, Yeh CC, Oberholzer J, Lei J, Chen T, Lian M, Markmann JF, Alvarez A, Linetsky E, Ricordi C, Balamurugan AN, Loganathan G, Wilhelm JJ, Hering BJ, Bottino R, Trucco M, Liu C, Min Z, Li Y, Naji A, Fernandez LA, Ziemelis M, Danobeitia JS, Millis JM, Witkowski P. A Multicenter Study: North American Islet Donor Score in Donor Pancreas Selection for Human Islet Isolation for Transplantation. Cell Transplant. 2016; 25(8):1515-1523.
  13. Kaplan JA, Schecter SC, Rogers SJ, Lin MYC, Posselt AM, Carter JT. Expanded indications for bariatric surgery: should patients on chronic steroids be offered bariatric procedures? Surg Obes Relat Dis. 2017 Jan; 13(1):35-40.
  14. Schafer AL, Weaver CM, Black DM, Wheeler AL, Chang H, Szefc GV, Stewart L, Rogers SJ, Carter JT, Posselt AM, Shoback DM, Sellmeyer DE. Intestinal Calcium Absorption Decreases Dramatically After Gastric Bypass Surgery Despite Optimization of Vitamin D Status. J Bone Miner Res. 2015 Aug; 30(8):1377-85.
  15. Tai DS, Shen N, Szot GL, Posselt A, Feduska NJ, Habashy A, Clerkin B, Core E, Busuttil RW, Hines OJ, Reber HA, Lipshutz GS. Autologous islet transplantation with remote islet isolation after pancreas resection for chronic pancreatitis. JAMA Surg. 2015 Feb; 150(2):118-24.
  16. Ahearn AJ, Parekh JR, Posselt AM. Islet transplantation for Type 1 diabetes: where are we now? Expert Rev Clin Immunol. 2015 Jan; 11(1):59-68.
  17. Carter J, Elliott S, Kaplan J, Lin M, Posselt A, Rogers S. Predictors of hospital stay following laparoscopic gastric bypass: analysis of 9,593 patients from the National Surgical Quality Improvement Program. Surg Obes Relat Dis. 2015 Mar-Apr; 11(2):288-94.
  18. Lin MY, Tavakol MM, Sarin A, Amirkiai SM, Rogers SJ, Carter JT, Posselt AM. Laparoscopic sleeve gastrectomy is safe and efficacious for pretransplant candidates. Surg Obes Relat Dis. 2013 Sep-Oct; 9(5):653-8.
  19. Barton FB, Rickels MR, Alejandro R, Hering BJ, Wease S, Naziruddin B, Oberholzer J, Odorico JS, Garfinkel MR, Levy M, Pattou F, Berney T, Secchi A, Messinger S, Senior PA, Maffi P, Posselt A, Stock PG, Kaufman DB, Luo X, Kandeel F, Cagliero E, Turgeon NA, Witkowski P, Naji A, O'Connell PJ, Greenbaum C, Kudva YC, Brayman KL, Aull MJ, Larsen C, Kay TW, Fernandez LA, Vantyghem MC, Bellin M, Shapiro AM. Improvement in outcomes of clinical islet transplantation: 1999-2010. Diabetes Care. 2012 Jul; 35(7):1436-45.
  20. Lin MY, Tavakol MM, Sarin A, Amirkiai SM, Rogers SJ, Carter JT, Posselt AM. Safety and feasibility of sleeve gastrectomy in morbidly obese patients following liver transplantation. Surg Endosc. 2013 Jan; 27(1):81-5.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.