Robert Lustig, MD

Pediatric endocrinologist

Dr. Robert Lustig, a pediatric endocrinologist at UCSF Benioff Children's Hospital, is nationally recognized in the field of neuroendocrinology, with an emphasis on the regulation of energy balance by the central nervous system. He is interested in how biochemical, neural, hormonal and genetic influences contribute to obesity in children and adults. He defined a syndrome of vagally mediated beta-cell hyperactivity that leads to excessive production of insulin and obesity, which may occur in up to 20 percent of the obese population and is treatable with insulin suppression. He also is studying the association between hyperinsulinemia, or the presence of excess insulin in the blood, and cardiovascular disease and is developing methods to evaluate and prevent this in children.

Lustig earned a bachelor's degree from the Massachusetts Institute of Technology (MIT) and a medical degree from Cornell University Medical College. He completed a pediatric residency at St. Louis Children's Hospital and a clinical fellowship in pediatric endocrinology at UCSF. From there, he spent six years as a postdoctoral fellow in neuroendocrinology at Rockefeller University in New York. Lustig is a professor of clinical pediatrics in the Division of Endocrinology at UCSF.


Endocrinology Clinic
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-7337
Fax: (415) 476-8214

Pediatric Brain Tumor Center
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-2986
Fax: (415) 353-2657

Conditions & Treatments

More about Robert Lustig


Cornell University Medical College 1980


St. Louis Children's Hospital, Pediatrics 1983


UCSF Medical Center, Pediatric Endocrinology 1984
Rockefeller University, Neuroendocrinology 1986

Selected Research and Publications

  1. Laraia BA, Adler NE, Coleman-Phox K, Vieten C, Mellin L, Kristeller JL, Thomas M, Stotland NE, Lustig RH, Dallman MF, Hecht FM, Bush NR, de Groat CL, Epel E. Novel Interventions to Reduce Stress and Overeating in Overweight Pregnant Women: A Feasibility Study. Matern Child Health J. 2018 May; 22(5):670-678.
  2. Rathore S, Akbari H, Doshi J, Shukla G, Rozycki M, Bilello M, Lustig R, Davatzikos C. Radiomic signature of infiltration in peritumoral edema predicts subsequent recurrence in glioblastoma: implications for personalized radiotherapy planning. J Med Imaging (Bellingham). 2018 Apr; 5(2):021219.
  3. Perito ER, Phelps A, Vase T, Feldstein VA, Lustig RH, Rosenthal P. Subclinical Atherosclerosis in Pediatric Liver Transplant Recipients: Carotid and Aorta Intima-Media Thickness and Their Predictors. J Pediatr. 2018 Feb; 193:119-127.e1.
  4. Vogel J, Both S, Kirk M, Chao HH, Bagatell R, Li Y, Womer R, Balamuth N, Reilly A, Kurtz G, Lustig R, Tochner Z, Hill-Kayser C. Proton therapy for pediatric head and neck malignancies. Pediatr Blood Cancer. 2018 Feb; 65(2).
  5. Lustig RH. Ethical Considerations for Nutrition Counseling About Processed Food-Reply. JAMA Pediatr. 2017 Sep 01; 171(9):914-915.
  6. Stigler FL, Lustig RH, Moser AM. Exercise Type in Dieting Obese Older Adults. N Engl J Med. 2017 08 10; 377(6):598-9.
  7. Vreman RA, Goodell AJ, Rodriguez LA, Porco TC, Lustig RH, Kahn JG. Health and economic benefits of reducing sugar intake in the USA, including effects via non-alcoholic fatty liver disease: a microsimulation model. BMJ Open. 2017 Aug 03; 7(8):e013543.
  8. Perito ER, Vase T, Ramachandran R, Phelps A, Jen KY, Lustig RH, Feldstein VA, Rosenthal P. Hepatic steatosis after pediatric liver transplant. Liver Transpl. 2017 Jul; 23(7):957-967.
  9. Schwarz JM, Noworolski SM, Erkin-Cakmak A, Korn NJ, Wen MJ, Tai VW, Jones GM, Palii SP, Velasco-Alin M, Pan K, Patterson BW, Gugliucci A, Lustig RH, Mulligan K. Effects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children With Obesity. Gastroenterology. 2017 09; 153(3):743-752.
  10. Lustig RH. Processed Food-An Experiment That Failed. JAMA Pediatr. 2017 Mar 01; 171(3):212-214.
  11. Harley KG, Rauch SA, Chevrier J, Kogut K, Parra KL, Trujillo C, Lustig RH, Greenspan LC, Sjödin A, Bradman A, Eskenazi B. Association of prenatal and childhood PBDE exposure with timing of puberty in boys and girls. Environ Int. 2017 03; 100:132-138.
  12. Perito ER, Lustig RH, Rosenthal P. Prediabetes in Pediatric Recipients of Liver Transplant: Mechanism and Risk Factors. J Pediatr. 2017 Mar; 182:223-231.e3.
  13. Eskenazi B, Rauch SA, Tenerelli R, Huen K, Holland NT, Lustig RH, Kogut K, Bradman A, Sjödin A, Harley KG. In utero and childhood DDT, DDE, PBDE and PCBs exposure and sex hormones in adolescent boys: The CHAMACOS study. Int J Hyg Environ Health. 2017 04; 220(2 Pt B):364-372.
  14. Lustig RH. Fructose and Nonalcoholic Fatty Liver Disease J Calif Dent Assoc. 2016 10 13; 44(10):613-17.
  15. Lustig RH. Sickeningly Sweet: Does Sugar Cause Type 2 Diabetes? Yes. Can J Diabetes. 2016 Aug; 40(4):282-6.
  16. Perito ER, Lustig RH, Rosenthal P. Metabolic Syndrome Components After Pediatric Liver Transplantation: Prevalence and the Impact of Obesity and Immunosuppression. Am J Transplant. 2016 06; 16(6):1909-16.
  17. Daubenmier J, Moran PJ, Kristeller J, Acree M, Bacchetti P, Kemeny ME, Dallman M, Lustig RH, Grunfeld C, Nixon DF, Milush JM, Goldman V, Laraia B, Laugero KD, Woodhouse L, Epel ES, Hecht FM. Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial. Obesity (Silver Spring). 2016 Apr; 24(4):794-804.
  18. Rodríguez LA, Madsen KA, Cotterman C, Lustig RH. Added sugar intake and metabolic syndrome in US adolescents: cross-sectional analysis of the National Health and Nutrition Examination Survey 2005-2012. Public Health Nutr. 2016 Sep; 19(13):2424-34.
  19. Mason AE, Epel ES, Aschbacher K, Lustig RH, Acree M, Kristeller J, Cohn M, Dallman M, Moran PJ, Bacchetti P, Laraia B, Hecht FM, Daubenmier J. Reduced reward-driven eating accounts for the impact of a mindfulness-based diet and exercise intervention on weight loss: Data from the SHINE randomized controlled trial. Appetite. 2016 May 01; 100:86-93.
  20. Lustig RH. Response to "Metabolic improvement with fructose restriction: Is it the fructose or the weight loss?". Obesity (Silver Spring). 2016 Mar; 24(3):550.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.