Anna Bakardjiev, MD

Pediatric infectious disease physician

Dr. Anna I. Bakardjiev is a pediatric infectious disease specialist at UCSF Benioff Children's Hospital who treats patients with all pediatric infectious diseases. She is particularly interested in congenital infections. In her research, she is focused on maternal-fetal infections, intracellular pathogens and innate immune responses to infections.

She earned a medical degree at the Medizinische Hocschule in Hanover, Germany. She also completed a residency at UCSF Benioff Children's Hospital and a fellowship at Children's Hospital of Oakland. Bakardjiev is a member of the American Society of Microbiology, Infectious Diseases Society of America, Pediatric Infectious Diseases Society and Society for Pediatric Research She is an assistant professor in residence in Pediatrics at UCSF.


Infectious Diseases Clinic
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-2813
Fax (in advance of appointment): (415) 476-1343
Fax (day of appointment): (415) 353-2466

More about Anna Bakardjiev


Medizzinsche Hochschule Hannover School of Medicine 1995


UCSF Medical Center, Pediatrics 2000
Children's Hospital, Oakland, Infectious Disease 2003

Selected Research and Publications

  1. Rizzuto G, Tagliani E, Manandhar P, Erlebacher A, Bakardjiev AI. Limited Colonization Undermined by Inadequate Early Immune Responses Defines the Dynamics of Decidual Listeriosis. Infect Immun. 2017 Aug; 85(8).
  2. Faralla C, Rizzuto GA, Lowe DE, Kim B, Cooke C, Shiow LR, Bakardjiev AI. InlP, a New Virulence Factor with Strong Placental Tropism. Infect Immun. 2016 Dec; 84(12):3584-3596.
  3. Rizzuto GA, Kapidzic M, Gormley M, Bakardjiev AI. Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface. J Vis Exp. 2016 Jul 21; (113).
  4. Vigliani MB, Bakardjiev AI. Intracellular Organisms as Placental Invaders. Fetal Matern Med Rev. 2014 Nov; 25(3-4):332-338.
  5. Bakardjiev A. Immunology: Stillbirth prevented by signal blockade. Nature. 2015 Apr 30; 520(7549):627-8.
  6. Vigliani MB, Bakardjiev AI. First trimester typhoid Fever with vertical transmission of salmonella typhi, an intracellular organism. Case Rep Med. 2013; 2013:973297.
  7. Zeldovich VB, Clausen CH, Bradford E, Fletcher DA, Maltepe E, Robbins JR, Bakardjiev AI. Placental syncytium forms a biophysical barrier against pathogen invasion. PLoS Pathog. 2013; 9(12):e1003821.
  8. Zeldovich VB, Bakardjiev AI. Host defense and tolerance: unique challenges in the placenta. PLoS Pathog. 2012; 8(8):e1002804.
  9. Wasilewski M, Semenzato M, Rafelski SM, Robbins J, Bakardjiev AI, Scorrano L. Optic atrophy 1-dependent mitochondrial remodeling controls steroidogenesis in trophoblasts. Curr Biol. 2012 Jul 10; 22(13):1228-34.
  10. Robbins JR, Bakardjiev AI. Pathogens and the placental fortress. Curr Opin Microbiol. 2012 Feb; 15(1):36-43.
  11. Melton-Witt JA, Rafelski SM, Portnoy DA, Bakardjiev AI. Oral infection with signature-tagged Listeria monocytogenes reveals organ-specific growth and dissemination routes in guinea pigs. Infect Immun. 2012 Feb; 80(2):720-32.
  12. Robbins JR, Zeldovich VB, Poukchanski A, Boothroyd JC, Bakardjiev AI. Tissue barriers of the human placenta to infection with Toxoplasma gondii. Infect Immun. 2012 Jan; 80(1):418-28.
  13. Zeldovich VB, Robbins JR, Kapidzic M, Lauer P, Bakardjiev AI. Invasive extravillous trophoblasts restrict intracellular growth and spread of Listeria monocytogenes. PLoS Pathog. 2011 Mar; 7(3):e1002005.
  14. Maltepe E, Bakardjiev AI, Fisher SJ. The placenta: transcriptional, epigenetic, and physiological integration during development. J Clin Invest. 2010 Apr; 120(4):1016-25.
  15. Robbins JR, Skrzypczynska KM, Zeldovich VB, Kapidzic M, Bakardjiev AI. Placental syncytiotrophoblast constitutes a major barrier to vertical transmission of Listeria monocytogenes. PLoS Pathog. 2010 Jan 22; 6(1):e1000732.
  16. Bakardjiev AI, Theriot JA, Portnoy DA. Listeria monocytogenes traffics from maternal organs to the placenta and back. PLoS Pathog. 2006 Jun; 2(6):e66.
  17. Bakardjiev AI, Stacy BA, Portnoy DA. Growth of Listeria monocytogenes in the guinea pig placenta and role of cell-to-cell spread in fetal infection. J Infect Dis. 2005 Jun 01; 191(11):1889-97.
  18. Bakardjiev AI, Stacy BA, Fisher SJ, Portnoy DA. Listeriosis in the pregnant guinea pig: a model of vertical transmission. Infect Immun. 2004 Jan; 72(1):489-97.
  19. Wallin JJ, Liang L, Bakardjiev A, Sha WC. Enhancement of CD8+ T cell responses by ICOS/B7h costimulation. J Immunol. 2001 Jul 01; 167(1):132-9.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.