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Home > Doctors > Thomas K. Shimotake

Thomas K. Shimotake, M.D.

Co-director of the Neurointensive Care Nursery

Dr. Thomas Shimotake is a neonatologist in the William H. Tooley Intensive Care Unit, where he cares for newborns ranging from extremely premature infants to full term babies with severe birth defects. He also is co-director of the Neurointensive Care Nursery (NICN), where he and the NICN team have developed new protocols, based on research, to treat babies at risk for brain injuries that were previously thought to be untreatable.

His research interests include neonatal lung diseases such as respiratory distress syndrome, a condition that afflicts premature babies; brain injury and repair in newborns; and simulation-based training in pediatrics for medical students and residents. He is an assistant clinical professor of pediatrics at UCSF and the fellowship training director for Neonatal-Perinatal Medicine. He's a fellow of the American Academy of Pediatrics and a member of their Perinatal Section. He's also a member of the California Association of Neonatologists.

Clinics

Intensive Care Nursery
505 Parnassus Ave., Fifteenth Floor
San Francisco, CA 94143-0210
Phone: (415) 353-1565

Neuro-Intensive Care Nursery
505 Parnassus Ave., 15th floor
San Francisco, CA 94143
Phone: (415) 353-1565

Conditions & Treatments

More about Thomas K. Shimotake

Additional Languages

Japanese

Education

University of Illinois School of Medicine 1997

Residencies

University of Chicago Medical Center, Pediatrics 2000

Fellowships

University of Chicago Medical Center, Neonatology 2003

Selected Research and Publications

  1. Shue EH, Soares B, Courtier J, Hogue J, Shimotake T, Mackenzie TC. Type IV intestinal atresia, congenital bilateral perisylvian syndrome, and chronic pulmonary hypertension secondary to multiple vascular disruption syndrome in a monochorionic twin. J Pediatr Surg. 2012 Oct; 47(10):1938-42.
  2. Glass HC, Bonifacio SL, Shimotake T, Ferriero DM. Neurocritical care for neonates. Curr Treat Options Neurol. 2011 Dec; 13(6):574-89.
  3. Hogeling M, Meddles K, Berk DR, Bruckner AL, Shimotake TK, Cohen RS, Frieden IJ. Extensive subcutaneous fat necrosis of the newborn associated with therapeutic hypothermia. Pediatr Dermatol. 2012 Jan-Feb; 29(1):59-63.
  4. Glass HC, Bonifacio SL, Peloquin S, Shimotake T, Sehring S, Sun Y, Sullivan J, Rogers E, Barkovich AJ, Rowitch D, Ferriero DM. Neurocritical care for neonates. Neurocrit Care. 2010 Jun; 12(3):421-9.
  5. Baldán A, Tarr P, Vales CS, Frank J, Shimotake TK, Hawgood S, Edwards PA. Deletion of the transmembrane transporter ABCG1 results in progressive pulmonary lipidosis. J Biol Chem. 2006 Sep 29; 281(39):29401-10.
  6. Shimotake TK, Izhar FM, Rumilla K, Li J, Tan A, Page K, Brasier AR, Schreiber MD, Hershenson MB. Interleukin (IL)-1 beta in tracheal aspirates from premature infants induces airway epithelial cell IL-8 expression via an NF-kappa B dependent pathway. Pediatr Res. 2004 Dec; 56(6):907-13.
  7. Tomiyama H, Shimotake T, Ono S, Kimura O, Tokiwa K, Iwai N. Relationship between the type of RET/GDNF/NTN or SOX10 gene mutations and long-term results after surgery for total colonic aganglionosis with small bowel involvement. J Pediatr Surg. 2001 Nov; 36(11):1685-8.
  8. Bitoh Y, Shimotake T, Kubota Y, Kimura O, Iwai N. Impaired distribution of retinoic acid receptors in the hindgut-tailgut region of murine embryos with anorectal malformations. J Pediatr Surg. 2001 Feb; 36(2):377-80.
  9. Inoue K, Shimotake T, Inoue K, Tokiwa K, Iwai N. Mutational analysis of the RET proto-oncogene in a kindred with multiple endocrine neoplasia type 2A and Hirschsprung's disease. J Pediatr Surg. 1999 Oct; 34(10):1552-4.
  10. Shimotake T, Furukawa T, Inoue K, Iwai N, Takeuchi Y. Familial occurrence of intestinal obstruction in children with the syndrome of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS). J Pediatr Surg. 1998 Dec; 33(12):1837-9.
  11. Shimotake T, Kubota Y, Inoue K, Yanagihara J, Iwai N. Absence of rectoanal inhibitory reflex in a child with multiple endocrine neoplasia type 2B. J Pediatr Surg. 1998 Aug; 33(8):1268-71.
  12. Kubota Y, Shimotake T, Yanagihara J, Iwai N. Development of anorectal malformations using etretinate. J Pediatr Surg. 1998 Jan; 33(1):127-9.
  13. Shimotake T, Iwai N, Inoue K, Kimura T, Ichikawa D, Abe T, Inazawa J. Germline mutation of the RET proto-oncogene in children with total intestinal aganglionosis. J Pediatr Surg. 1997 Mar; 32(3):498-500.
  14. Shimotake T, Iwai N, Inoue K, Inazawa J, Nishisho I. Germline mutations of the RET proto-oncogene in pedigree with MEN type 2A: DNA analysis and its implications for pediatric surgery. J Pediatr Surg. 1996 Jun; 31(6):779-81.
  15. Shimotake T, Iwai N, Yanagihara J, Deguchi E, Fushiki S. Impaired proliferative activity of mesenchymal cells affects the migratory pathway for neural crest cells in the developing gut of mutant murine embryos. J Pediatr Surg. 1995 Mar; 30(3):445-7.
  16. Iwai N, Nagashima M, Shimotake T, Iwata G. Biofeedback therapy for fecal incontinence after surgery for anorectal malformations: preliminary results. J Pediatr Surg. 1993 Jun; 28(6):863-6.
  17. Shimotake T, Iwai N, Yanagihara J, Tokiwa K, Fushiki S. Biliary tract complications in patients with hypoganglionosis and chronic idiopathic intestinal pseudoobstruction syndrome. J Pediatr Surg. 1993 Feb; 28(2):189-92.
  18. Nagashima M, Iwai N, Yanagihara J, Shimotake T. Motility and sensation of the rectosigmoid and the rectum in patients with anorectal malformations. J Pediatr Surg. 1992 Oct; 27(10):1273-7.
  19. Shimotake T, Iwai N, Yanagihara J, Tokiwa K, Tanaka N, Yamamoto M, Takai S. Prediction of affected MEN2A gene carriers by DNA linkage analysis for early total thyroidectomy: a progress in clinical screening program for children with hereditary cancer syndrome. J Pediatr Surg. 1992 Apr; 27(4):444-6.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.

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