Maria Roberta Cilio, M.D., Ph.D.

Pediatric neurologist

Dr. Maria Roberta Cilio is a pediatric and neonatal epileptologist who serves as the director of research in pediatric epilepsy at the UCSF Epilepsy Center. Cilio is an internationally renowned expert in the diagnosis and treatment of early-onset epilepsies and epileptic encephalopathies. Her research aims to improve the diagnosis and treatment of rare epilepsies, particularly those that are genetic, which occur in the very first years of life. Cilio serves as project leader for research funded by the European Commission ERA-Net for Research Programmes on Rare Diseases and the Italian Ministry of Health. The research aims to develop continuous EEG monitoring in neonates at risk for epilepsy and identify the genetic defects in infants with epilepsy with the goal of developing targeted treatment strategies.

Cilio received her medical degree from the University of Rome La Sapienza in Italy. Subsequently, she completed a residency in pediatrics and pediatric neurology at the Catholic University of Louvain in Brussels, Belgium and University of Rome La Sapienza, followed by a fellowship in pediatric epilepsy and clinical neurophysiology at the Bambino Gesú Hospital and Research Institute of Rome. Cilio then earned a doctorate at Boston Children's Hospital, Harvard Medical School, which focused on the structural and functional consequences of seizures in the immature brain. Cilio is professor in the Department of Neurology at UCSF, where she received the Presidential Chair Award from the Office of the President.


Epilepsy Center
1825 Fourth St., Fifth Floor
San Francisco, CA 94158
Phone: (415) 353-2437

Conditions & Treatments

More about Maria Roberta Cilio

Additional Languages



Universita Degli Studi di Roma La Sapienza 1988


Catholic University of Louvain, Pediatrics 1989
University of Rome La Sapienza, Pediatric Neurology 1993


Bambino Gesú Children's Hospital and Research Institute, Pediatric Epilepsy 1997

Selected Research and Publications

  1. Barcia G, Fleming MR, Deligniere A, Gazula VR, Brown MR, Langouet M, Chen H, Kronengold J, Abhyankar A, Cilio R, Nitschke P, Kaminska A, Boddaert N, Casanova JL, Desguerre I, Munnich A, Dulac O, Kaczmarek LK, Colleaux L, Nabbout R. De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy. Nat Genet. 2012 Nov; 44(11):1255-9.
  2. Borsellino A, Giorlandino C, Malena S, Trucchi A, Cilio R, Bagolan P. Early neurologic complications of pulmonary arteriovenous malformation in a newborn: an indication for surgical resection. J Pediatr Surg. 2006 Feb; 41(2):453-5.
  3. Soriani S, Scarpa P, Voghenzi A, De Carlo L, Cilio R. Moyamoya disease in childhood: a familial case report. Childs Nerv Syst. 1993 Jul; 9(4):215-9.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.