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Igor Barani, M.D.

Radiation cancer specialist

Dr. Igor Barani is a radiation cancer specialist with a particular interest in the treatment of cancer of the brain and central nervous system. He specializes in the use of radiosurgical techniques, such as the Cyberknife, to treat adults and children with malignant and benign conditions. He's also interested in the development and implementation of new treatments for brain tumors, especially treatments that preserve brain and other neurologic function.

Barani's research revolves around neural stem cells and their potential roles in the development of gliomas, which is cancer of the brain or spine, as well as neurocognitive decline after treatment. The study of treatment-related side effects is increasingly important as the number of long-term survivors of childhood and adult brain tumors increases with improved therapies. Barani is exploring neural stem cell biology and modern treatment techniques to benefit patients with central nervous system tumors. He is an assistant professor of radiation oncology at UCSF.

Clinics

Radiation Oncology at Parnassus
505 Parnassus Ave., Suite L75
San Francisco, CA 94143-0226
Appointments, Referrals: (415) 353-9807
New Patient Coordinator: (415) 353-8335
General: (415) 353-8900

Conditions & Treatments

More about Igor Barani

Education

SUNY, Syracuse School of Medicine 2003

Residencies

Virginia Commonwealth University School of Medicine, Radiation Oncology 2008

Selected Research and Publications

  1. Ma L, Sahgal A, Larson DA, Pinnaduwage D, Fogh S, Barani I, Nakamura J, McDermott M, Sneed P. Impact of millimeter-level margins on peripheral normal brain sparing for gamma knife radiosurgery. Int J Radiat Oncol Biol Phys. 2014 May 1; 89(1):206-13.
  2. Kaur G, Sayegh ET, Larson A, Bloch O, Madden M, Sun MZ, Barani IJ, James CD, Parsa AT. Adjuvant radiotherapy for atypical and malignant meningiomas: a systematic review. Neuro Oncol. 2014 May; 16(5):628-36.
  3. Kaley T, Barani I, Chamberlain M, McDermott M, Panageas K, Raizer J, Rogers L, Schiff D, Vogelbaum M, Weber D, Wen P. Historical benchmarks for medical therapy trials in surgery- and radiation-refractory meningioma: a RANO review. Neuro Oncol. 2014 Jun; 16(6):829-40.
  4. Jian BJ, Kaur G, Sayegh ET, Bloch O, Parsa AT, Barani IJ. Fractionated radiation therapy for vestibular schwannoma. J Clin Neurosci. 2014 Jul; 21(7):1083-8.
  5. Garcia RM, Ivan ME, Oh T, Barani I, Parsa AT. Intraventricular neurocytomas: A systematic review of stereotactic radiosurgery and fractionated conventional radiotherapy for residual or recurrent tumors. Clin Neurol Neurosurg. 2014 Feb; 117:55-64.
  6. Lin NU, Lee EQ, Aoyama H, Barani IJ, Baumert BG, Brown PD, Camidge DR, Chang SM, Dancey J, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Lamborn KR, Linskey ME, Macdonald DR, Margolin K, Mehta MP, Schiff D, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wefel JS, Wen PY. Challenges relating to solid tumour brain metastases in clinical trials, part 1: patient population, response, and progression. A report from the RANO group. Lancet Oncol. 2013 Sep; 14(10):e396-406.
  7. Lin NU, Wefel JS, Lee EQ, Schiff D, van den Bent MJ, Soffietti R, Suh JH, Vogelbaum MA, Mehta MP, Dancey J, Linskey ME, Camidge DR, Aoyama H, Brown PD, Chang SM, Kalkanis SN, Barani IJ, Baumert BG, Gaspar LE, Hodi FS, Macdonald DR, Wen PY. Challenges relating to solid tumour brain metastases in clinical trials, part 2: neurocognitive, neurological, and quality-of-life outcomes. A report from the RANO group. Lancet Oncol. 2013 Sep; 14(10):e407-16.
  8. Barani IJ, Larson DA, Berger MS. Future directions in treatment of brain metastases. Surg Neurol Int. 2013; 4(Suppl 4):S220-30.
  9. Wahl M, Hwang A, Nakamura J, Barani I, Fogh S, Sneed P, McDermott M, Sahgal A, Ma L. Individual beam sharpening improves composite dose fall-off near a target for non-isocentric cyberknife radiosurgery. Technol Cancer Res Treat. 2013 Aug; 12(4):341-8.
  10. Huang T, Mueller S, Rutkowski MJ, Han SJ, Bloch O, Barani IJ, Parsa AT, Chang SM. Multidisciplinary care of patients with brain tumors. Surg Oncol Clin N Am. 2013 Apr; 22(2):161-78.
  11. Johnson J, Barani IJ. Radiotherapy for malignant tumors of the skull base. Neurosurg Clin N Am. 2013 Jan; 24(1):125-35.
  12. Fogh S, Ma L, Gupta N, Sahgal A, Nakamura JL, Barani I, Sneed PK, McDermott M, Larson DA. High-precision volume-staged Gamma Knife surgery and equivalent hypofractionation dose schedules for treating large arteriovenous malformations. J Neurosurg. 2012 Dec; 117 Suppl:115-9.
  13. Jafri NF, Clarke JL, Weinberg V, Barani IJ, Cha S. Relationship of glioblastoma multiforme to the subventricular zone is associated with survival. Neuro Oncol. 2013 Jan; 15(1):91-6.
  14. Bloch O, Sun M, Kaur G, Barani IJ, Parsa AT. Fractionated radiotherapy for optic nerve sheath meningiomas. J Clin Neurosci. 2012 Sep; 19(9):1210-5.
  15. Mills SA, Oh MC, Rutkowski MJ, Sughrue ME, Barani IJ, Parsa AT. Supratentorial hemangioblastoma: clinical features, prognosis, and predictive value of location for von Hippel-Lindau disease. Neuro Oncol. 2012 Aug; 14(8):1097-104.
  16. Han SJ, Oh MC, Sughrue ME, Rutkowski MJ, Aranda D, Barani IJ, Parsa AT. The effect of the 2003 Consensus Reporting Standards on publications describing patients with vestibular schwannoma treated with stereotactic radiosurgery. J Clin Neurosci. 2012 Aug; 19(8):1144-7.
  17. Descovich M, Ma L, Chuang CF, Larson DA, Barani IJ. Comparison between prone and supine patient setup for spine stereotactic body radiosurgery. Technol Cancer Res Treat. 2012 Jun; 11(3):229-36.
  18. Ivan ME, Cheng JS, Kaur G, Sughrue ME, Clark A, Kane AJ, Aranda D, McDermott M, Barani IJ, Parsa AT. Association of morbidity with extent of resection and cavernous sinus invasion in sphenoid wing meningiomas. J Neurol Surg B Skull Base. 2012 Feb; 73(1):76-83.
  19. Caballero JA, Sneed PK, Lamborn KR, Ma L, Denduluri S, Nakamura JL, Barani IJ, McDermott MW. Prognostic factors for survival in patients treated with stereotactic radiosurgery for recurrent brain metastases after prior whole brain radiotherapy. Int J Radiat Oncol Biol Phys. 2012 May 1; 83(1):303-9.
  20. Ma L, Lee L, Barani I, Hwang A, Fogh S, Nakamura J, McDermott M, Sneed P, Larson DA, Sahgal A. Shot sequencing based on biological equivalent dose considerations for multiple isocenter Gamma Knife radiosurgery. Phys Med Biol. 2011 Nov 21; 56(22):7247-56.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.