Neuroblastoma
Signs and Symptoms

The most common symptoms of neuroblastoma are caused by pressure from the tumor or bone pain from cancer that has spread to the bone and bone marrow. Symptoms may include:

• Protruding eyes and dark circles around the eyes caused by cancer that has spread to the area behind the eye


• Paralaysis from neuroblastoma that compresses the spinal cord


• Fever, anemia and high blood pressure are occasionally experienced

Other less common symptoms include:

• Severe diarrhea
• Uncoordinated or jerky muscle movements
• Uncontrollable eye movement

Symptoms also may include:

• A firm mass in the abdomen
• Difficulty breathing
• Weight loss
• Fever
• Bone pain
• Difficulty swallowing

Reviewed by health care specialists at UCSF Benioff Children's Hospital.
Last updated July 14, 2010