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Home > Doctors > Michael R. Harrison

Michael R. Harrison, M.D.

Fetal and pediatric surgeon

Dr. Michael Harrison is director emeritus and co-founder of the Fetal Treatment Center at UCSF Benioff Children's Hospital. He is an internationally known expert in fetal surgery, an area he helped pioneer with his colleagues at UCSF. For more than 25 years, he has studied how life-threatening fetal abnormalities alter normal physical processes. He developed techniques for both open surgery and minimally invasive surgery to repair many birth defects. Harrison's team also developed in utero stem cell transplantation to treat immune system deficiencies, enzyme deficiencies and abnormal hemoglobin in the blood.

Harrison graduated cum laude from Yale University and magna cum laude from Harvard Medical School. He completed surgical training at Massachusetts General Hospital in Boston and a pediatric surgery fellowship at Children's Hospital of Los Angeles. He is a professor emeritus of surgery, pediatrics, obstetrics, gynecology and reproductive sciences.

Clinics

Fetal Treatment Center
400 Parnassus Ave., A123
San Francisco, CA 94143
Phone: (415) 476-0445

Pediatric Prepare Program
400 Parnassus Ave., Third Floor, Room A-334
San Francisco, CA 94143-0210
Phone: (415) 353-1150

Conditions & Treatments

More about Michael R. Harrison

Additional Languages

Spanish

Education

Harvard University School of Medicine 1969

Residencies

Massachusetts General Hospital, General Surgery 1975

Fellowships

Los Angeles Children's Hospital, Pediatric Surgery 1978

Selected Research and Publications

  1. Antonarakis ES, Heath EI, Posadas EM, Yu EY, Harrison MR, Bruce JY, Cho SY, Wilding GE, Fetterly GJ, Hangauer DG, Kwan MF, Dyster LM, Carducci MA. A phase 2 study of KX2-391, an oral inhibitor of Src kinase and tubulin polymerization, in men with bone-metastatic castration-resistant prostate cancer. Cancer Chemother Pharmacol. 2013 Apr; 71(4):883-92.
  2. Harrison MR, Wong TZ, Armstrong AJ, George DJ. Radium-223 chloride: a potential new treatment for castration-resistant prostate cancer patients with metastatic bone disease. Cancer Manag Res. 2013; 5:1-14.
  3. Plantmason LR, Xu G, Harrison MR, Maa J. Novel use of a magnet to help remove metallic foreign bodies from the gastrointestinal tract. Am Surg. 2012 Nov; 78(11):472-3.
  4. Inman BA, Harrison MR, George DJ. Novel immunotherapeutic strategies in development for renal cell carcinoma. Eur Urol. 2013 May; 63(5):881-9.
  5. Turnbull JD, Cobert J, Jaffe T, Harrison MR, George DJ, Armstrong AJ. Activity of single-agent bevacizumab in patients with metastatic renal cell carcinoma previously treated with vascular endothelial growth factor tyrosine kinase inhibitors. Clin Genitourin Cancer. 2013 Mar; 11(1):45-50.
  6. Lien CL, Harrison MR, Tuan TL, Starnes VA. Heart repair and regeneration: recent insights from zebrafish studies. Wound Repair Regen. 2012 Sep-Oct; 20(5):638-46.
  7. Baxendale S, Holdsworth CJ, Meza Santoscoy PL, Harrison MR, Fox J, Parkin CA, Ingham PW, Cunliffe VT. Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures. Dis Model Mech. 2012 Nov; 5(6):773-84.
  8. Gonzales KD, Douglas G, Pichakron KO, Kwiat DA, Gallardo SG, Encinas JL, Hirose S, Harrison MR. Magnamosis III: delivery of a magnetic compression anastomosis device using minimally invasive endoscopic techniques. J Pediatr Surg. 2012 Jun; 47(6):1291-5.
  9. Saadai P, Jelin EB, Nijagal A, Schecter SC, Hirose S, MacKenzie TC, Rand L, Goldstein R, Farrell J, Harrison M, Lee H. Long-term outcomes after fetal therapy for congenital high airway obstructive syndrome. J Pediatr Surg. 2012 Jun; 47(6):1095-100.
  10. Shue EH, Harrison M, Hirose S. Maternal-fetal surgery: history and general considerations. Clin Perinatol. 2012 Jun; 39(2):269-78.
  11. Harrison MR, Gonzales KD, Bratton BJ, Christensen D, Curran PF, Fechter R, Hirose S. Magnetic mini-mover procedure for pectus excavatum III: safety and efficacy in a Food and Drug Administration-sponsored clinical trial. J Pediatr Surg. 2012 Jan; 47(1):154-9.
  12. Leroy J, Perretta S, Diana M, Wall J, Lindner V, Harrison M, Marescaux J. An original endoluminal magnetic anastomotic device allowing pure NOTES transgastric and transrectal sigmoidectomy in a porcine model: proof of concept. Surg Innov. 2012 Jun; 19(2):109-16.
  13. Rosenbluth KH, Kwiat DA, Harrison MR, Kezirian EJ. Hyoid bone advancement for improving airway patency: cadaver study of a magnet-based system. Otolaryngol Head Neck Surg. 2012 Mar; 146(3):491-6.
  14. Harrison MR. Pharmacotherapy options in advanced renal cell carcinoma: what role for pazopanib? Clin Med Insights Oncol. 2011; 5:349-64.
  15. Liu G, Jeraj R, Vanderhoek M, Perlman S, Kolesar J, Harrison M, Simoncic U, Eickhoff J, Carmichael L, Chao B, Marnocha R, Ivy P, Wilding G. Pharmacodynamic study using FLT PET/CT in patients with renal cell cancer and other solid malignancies treated with sunitinib malate. Clin Cancer Res. 2011 Dec 15; 17(24):7634-44.
  16. Harrison MR, George DJ. Better late than early: FDG-PET imaging in metastatic renal cell carcinoma. Clin Cancer Res. 2011 Sep 15; 17(18):5841-3.
  17. Harrison MR. Tracheal occlusion works. Fetal Diagn Ther. 2011; 29(1):78-9.
  18. Harrison MR, Georgiou AS, Spaink HP, Cunliffe VT. The epigenetic regulator Histone Deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos. BMC Genomics. 2011; 12:24.
  19. Pichakron KO, Jelin EB, Hirose S, Curran PF, Jamshidi R, Stephenson JT, Fechter R, Strange M, Harrison MR. Magnamosis II: Magnetic compression anastomosis for minimally invasive gastrojejunostomy and jejunojejunostomy. J Am Coll Surg. 2011 Jan; 212(1):42-9.
  20. Lightman EG, Harrison MR, Cunliffe VT. Opposing actions of histone deacetylase 1 and Notch signalling restrict expression of erm and fgf20a to hindbrain rhombomere centres during zebrafish neurogenesis. Int J Dev Biol. 2011; 55(6):597-602.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.

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