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Home > Doctors > Tippi C. Mackenzie

Tippi C. Mackenzie, M.D.

Fetal and pediatric surgeon

Dr. Tippi MacKenzie, a pediatric surgeon at UCSF Benioff Children's Hospital and its Fetal Treatment Center, has a special interest in fetal surgery, advanced laparoscopy and endocrine and biliary surgery. MacKenzie is a member of the Biomedical Sciences Program and the Institute for Regeneration Medicine, with a research focus in in utero stem cell transplantation to treat genetic disease.

MacKenzie earned a medical degree at Stanford University and completed a general surgery residency at Brigham and Women's Hospital in Boston. She completed a pediatric surgery fellowship at the Children's Hospital of Philadelphia where she held a clinical appointment in General, Thoracic and Fetal Surgery. She is an assistant professor of surgery at UCSF.

Clinics

Fetal Treatment Center
400 Parnassus Ave., A123
San Francisco, CA 94143
Phone: (415) 476-0445

Pediatric Prepare Program
400 Parnassus Ave., Third Floor, Room A-334
San Francisco, CA 94143-0210
Phone: (415) 353-1150

Pediatric Surgery Clinic
400 Parnassus Ave., Suite A123
San Francisco, CA 94143
Phone: (415) 476-2538

Conditions & Treatments

More about Tippi C. Mackenzie

Education

Stanford School of Medicine 1997

Residencies

Brigham and Women's Hospital, Surgery 1999
Children's Hospital of Philadelphia, Pediatric Surgery 2002

Fellowships

Children's Hospital of Philadelphia, Pediatric Surgery 2007

Selected Research and Publications

  1. Nijagal A, Mackenzie TC. Clinical implications of maternal-fetal cellular trafficking. Semin Pediatr Surg. 2013 Feb; 22(1):62-5.
  2. Schecter SC, Courtier J, Cho SJ, Saadai P, Hirose S, Mackenzie TC, Miniati D. Hepatic portocholecystostomy for biliary atresia: A 25-year follow-up and review. J Pediatr Surg. 2013 Jan; 48(1):262-6.
  3. Shue EH, Soares B, Courtier J, Hogue J, Shimotake T, Mackenzie TC. Type IV intestinal atresia, congenital bilateral perisylvian syndrome, and chronic pulmonary hypertension secondary to multiple vascular disruption syndrome in a monochorionic twin. J Pediatr Surg. 2012 Oct; 47(10):1938-42.
  4. Nijagal A, Jelin E, Feldstein VA, Courtier J, Urisman A, Jones KD, Lee H, Hirose S, MacKenzie TC. The diagnosis and management of intradiaphragmatic extralobar pulmonary sequestrations: a report of 4 cases. J Pediatr Surg. 2012 Aug; 47(8):1501-5.
  5. Saadai P, Mackenzie TC. Increased maternal microchimerism after open fetal surgery. Chimerism. 2012 Jul 1; 3(3):69-71.
  6. Saadai P, Lee TH, Bautista G, Gonzales KD, Nijagal A, Busch MP, Kim CJ, Romero R, Lee H, Hirose S, Rand L, Miniati D, Farmer DL, MacKenzie TC. Alterations in maternal-fetal cellular trafficking after fetal surgery. J Pediatr Surg. 2012 Jun; 47(6):1089-94.
  7. Saadai P, Jelin EB, Nijagal A, Schecter SC, Hirose S, MacKenzie TC, Rand L, Goldstein R, Farrell J, Harrison M, Lee H. Long-term outcomes after fetal therapy for congenital high airway obstructive syndrome. J Pediatr Surg. 2012 Jun; 47(6):1095-100.
  8. Nijagal A, Flake AW, MacKenzie TC. In utero hematopoietic cell transplantation for the treatment of congenital anomalies. Clin Perinatol. 2012 Jun; 39(2):301-10.
  9. Nijagal A, Fleck S, MacKenzie TC. Maternal microchimerism in patients with biliary atresia: Implications for allograft tolerance. Chimerism. 2012 Apr-Jun; 3(2):37-9.
  10. Nijagal A, Fleck S, Hills NK, Feng S, Tang Q, Kang SM, Rosenthal P, MacKenzie TC. Decreased risk of graft failure with maternal liver transplantation in patients with biliary atresia. Am J Transplant. 2012 Feb; 12(2):409-19.
  11. Landsman L, Nijagal A, Whitchurch TJ, Vanderlaan RL, Zimmer WE, Mackenzie TC, Hebrok M. Pancreatic mesenchyme regulates epithelial organogenesis throughout development. PLoS Biol. 2011 Sep; 9(9):e1001143.
  12. Nijagal A, Le T, Wegorzewska M, Mackenzie TC. A mouse model of in utero transplantation. J Vis Exp. 2011; (47).
  13. Nijagal A, Wegorzewska M, Jarvis E, Le T, Tang Q, MacKenzie TC. Maternal T cells limit engraftment after in utero hematopoietic cell transplantation in mice. J Clin Invest. 2011 Feb; 121(2):582-92.
  14. Zaid HB, Rhee SJ, Hirose S, Mackenzie TC. Image of the month--quiz case. Gastric duplication cyst. Arch Surg. 2010 Oct; 145(10):1019, 1020.
  15. Jancelewicz T, Vu LT, Keller RL, Bratton B, Lee H, Farmer D, Harrison M, Miniati D, Mackenzie T, Hirose S, Nobuhara K. Long-term surgical outcomes in congenital diaphragmatic hernia: observations from a single institution. J Pediatr Surg. 2010 Jan; 45(1):155-60; discussion 160.
  16. Sabatino DE, Mackenzie TC, Peranteau W, Edmonson S, Campagnoli C, Liu YL, Flake AW, High KA. Persistent expression of hF.IX After tolerance induction by in utero or neonatal administration of AAV-1-F.IX in hemophilia B mice. Mol Ther. 2007 Sep; 15(9):1677-85.
  17. Keswani SG, Crombleholme TM, Rychik J, Tian Z, Mackenzie TC, Johnson MP, Wilson RD, Flake AW, Hedrick HL, Howell LJ, Adzick NS. Impact of continuous intraoperative monitoring on outcomes in open fetal surgery. Fetal Diagn Ther. 2005 Jul-Aug; 20(4):316-20.
  18. MacKenzie TC, Kobinger GP, Louboutin JP, Radu A, Javazon EH, Sena-Esteves M, Wilson JM, Flake AW. Transduction of satellite cells after prenatal intramuscular administration of lentiviral vectors. J Gene Med. 2005 Jan; 7(1):50-8.
  19. Bouchard S, MacKenzie TC, Radu AP, Hayashi S, Peranteau WH, Chirmule N, Flake AW. Long-term transgene expression in cardiac and skeletal muscle following fetal administration of adenoviral or adeno-associated viral vectors in mice. J Gene Med. 2003 Nov; 5(11):941-50.
  20. MacKenzie TC, Kobinger GP, Kootstra NA, Radu A, Sena-Esteves M, Bouchard S, Wilson JM, Verma IM, Flake AW. Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes. Mol Ther. 2002 Sep; 6(3):349-58.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.

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